Leigh MacMillan

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Microtubules act as cellular ‘rheostat’ to control insulin secretion

Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell.

Lung diseases expert Garcia set for Discovery Lecture

Joe G.N. “Skip” Garcia, M.D., recognized for developing novel therapies for critically ill patients with acute inflammatory lung disease, will deliver the next Flexner Discovery Lecture on Thursday, Dec. 10.

VUMC’s Baganz honored by Society for Neuroscience

For her contributions to public communication, outreach and education about neuroscience, Nicole Baganz, Ph.D., a postdoctoral fellow in Pharmacology, received the 2015 Next Generation Award from the Society for Neuroscience.

DNA sequence visualization

Study helps clarify components of DNA ‘copy machine’

Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery.

Detect and defend against pathogens

Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections.

Prenatal folic acid and asthma

The timing of folic acid-containing prescription filling during pregnancy was associated with childhood asthma, according to a new Vanderbilt study.

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