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Tool finds connections in genome data

Feb. 8, 2012—A new analytical tool points to genes that act together to increase disease risk.

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Treatment window for genetic disorder

Feb. 1, 2012—Treatment with a drug used to prevent organ rejection partially reverses the course of tuberous sclerosis, research in mice suggests.

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Drugs reverse lung cancer cell changes

Feb. 1, 2012—Drugs that target “epigenetic” changes may help treat or slow the progression of lung cancer.

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Protein repairs esophageal DNA damage

Jan. 25, 2012—A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer.

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Alcohol’s molecular mediators

Jan. 23, 2012—Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.

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Studies shed new light on how nitric oxide is produced

Jan. 20, 2012—The discovery of a previously unrecognized and pivotal role of enzyme ASL in nitric oxide production could potentially lead to new therapies for babies with pulmonary hypertension.

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Digestive disease research bolstered by grant renewal

Jan. 20, 2012—The Vanderbilt Digestive Disease Research Center celebrates its 10th anniversary this year with a second five-year renewal of its federal research grant.

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Pumping up the pancreas in pregnancy

Jan. 20, 2012—A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.

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Obesity genes linked to uterine cancer

Jan. 20, 2012—In addition to body mass index, genetic markers of obesity may provide value in predicting endometrial cancer risk.

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Number of heart transplants at VUMC on rise

Jan. 5, 2012—Vanderbilt University Medical Center usually performs about 15 heart transplants a year. Since August, however, the program has experienced a surge in the number of procedures. In five months there have been 19 transplantations, bringing the total number in 2011 to 25 adult heart transplants, with a 100 percent survival rate among adults. In fact,...

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Study applies random genotype sets to new disease

Jan. 5, 2012—A new study in the American Journal of Human Genetics, led by Vanderbilt researchers Josh Denny, M.D., M.S., and Dana Crawford, Ph.D., takes random volumes of human genotypes and matches them with data siphoned from de-identified medical records and sheds new light on the genetic basis of the common disease hypothyroidism. In a research lab,...

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Melatonin found to ease sleep woes in children with autism

Jan. 5, 2012—A new Vanderbilt study shows that the over-the-counter supplement melatonin is promising in helping children with autism spectrum disorders (ASD), and their families, sleep better. The study, published in the Journal of Autism and Developmental Disorders, contributes to the growing literature on supplemental melatonin for insomnia in ASD, according to lead author Beth Malow, M.D.,...

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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