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Aliquots Archives

Drug interaction causes hypotension

Mar. 28, 2019—A muscle relaxing-drug and inhibitors of the metabolic enzyme CYP1A2 interact to cause severely low blood pressure and should not be co-prescribed, Vanderbilt investigators caution.

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Unraveling endocytosis

Mar. 28, 2019—New discoveries by Jason MacGurn and colleagues further understanding of the complex machinery that cells use take up substances from outside the cell.

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New way to stimulate learning?

Mar. 14, 2019—Vagus nerve stimulation could be beneficial for treating Alzheimer’s disease and other forms of cognitive impairment, Vanderbilt research findings suggest.

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Correctly copying DNA

Mar. 14, 2019—A precise understanding of how the enzyme topoisomerase II cuts DNA could lead to better anti-cancer therapies.

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Exploring the brain’s white matter

Mar. 14, 2019—New comprehensive functional MRI measurements point to the need to update models for assessing brain white matter activity and physiology.

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Reprogramming cells for kidney repair

Mar. 14, 2019—Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.

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Lighting up colorectal cancer

Feb. 28, 2019—A nanobeacon imaging agent that binds specifically to colorectal cancer cells may aid the early detection of cancer during colonoscopy.

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Achilles’ heel for kidney cancer

Feb. 28, 2019—The discovery that kidney cells with mutations in a certain gene are sensitive to therapies called PI3K inhibitors opens new opportunities for applying precision medicine to cancer treatment.

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Personalized pain management

Feb. 28, 2019—Understanding how natural brain chemicals with pain-relieving properties interact with administered opioids may guide personalized approaches for pain management.

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Protein loss promotes cell migration

Feb. 28, 2019—The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.

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Probing H. pylori cancer protein

Feb. 14, 2019—Understanding how a bacterial protein that influences the risk of stomach cancer is produced could guide new strategies for treatment.

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The yin and yang of cell signaling

Feb. 14, 2019—Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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