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Aliquots Archives

Designing antibodies to fight the flu

Jan. 31, 2019—Vanderbilt investigators said their work shows that computational design can improve the ability of naturally occurring antibodies to recognize different flu strains and may hasten the development of more effective flu therapies and vaccines.

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New target for chronic kidney disease

Jan. 31, 2019—Preventing the formation of secretory structures that promote scarring in the kidney could offer new therapeutic options for a disease that affects millions of people worldwide.

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Signals from the “conveyor belt”

Jan. 17, 2019—Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.

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Pain relievers a risk for C. diff?

Jan. 17, 2019—A link between anti-inflammatory drugs such as ibuprofen and C. diff infection suggests caution against overusing such drugs in patients at high risk for infection.

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DNA’s on/off switch

Jan. 17, 2019—DNA-binding “switches” represent a fundamentally new method of communication between DNA-processing enzymes, Vanderbilt researchers propose.

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Building a pancreas

Jan. 17, 2019—Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.

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Lean vs. obese adipose tissue cells

Dec. 13, 2018—A greater understanding of the mechanisms and cell types involved in returning adipose (fatty) tissue to the lean state may lead to more effective treatments for obesity.

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Breast cancer-killing RIG

Dec. 13, 2018—A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.

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The exocyst dynamo

Dec. 13, 2018—New methods have revealed details of vesicle trafficking in cells and are applicable to any protein complexes, potentially revolutionizing our understanding of cell dynamics.

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RNA processing and antiviral immunity

Dec. 13, 2018—John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.

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Analyzing single-cell landscapes

Nov. 29, 2018—Vanderbilt researchers have developed a new tool for quantifying data from single-cell studies.

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Green tea and diabetes

Nov. 29, 2018—In a large population study of Chinese adults, Vanderbilt researchers found that green tea drinking increased risk of type 2 diabetes.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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