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antibiotics Archives

Effort to remove penicillin allergy labels seeing success

Oct. 17, 2019—A program in the Medical Intensive Care Unit has successfully removed penicillin allergy labels from more than 45 inpatients at high risk to receive antibiotics, but whose penicillin allergies were low risk.

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New test assists physicians with quicker treatment decisions for sepsis

Oct. 3, 2019—Rapid blood culture diagnostics for patients with bacterial bloodstream infections delivered final results in 12 hours versus the two to three days required for conventional testing.

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Gene identified that increases risk of antibiotic reaction

Feb. 28, 2019—Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

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New staph virulence factor

Jun. 28, 2018—Jun. 28, 2018—The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections.

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Records point to drug-drug interaction

May. 7, 2018—Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage.

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Amoxicillin alone better choice for pediatric pneumonia: study

Nov. 9, 2017—A combination of two antibiotics is often prescribed to treat community-acquired pneumonia in children, but a JAMA Pediatrics study is now showing that using just one of the two has the same benefit to patients in most cases.

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Novel insights to antibiotic targets

Sep. 29, 2017—New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

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Study tests shorter antibiotic course in children

Dec. 1, 2016—Researchers at Vanderbilt University Medical Center (VUMC) are leading a multicenter clinical trial to evaluate whether a shorter course of antibiotics — five days instead of 10 — is effective at treating community-acquired pneumonia (CAP) in children who show improvement after the first few days of taking antibiotics.

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Program seeks to optimize appropriate use of antibiotics

Nov. 10, 2016—Relying on a core team of physicians and pharmacists, the Vanderbilt Antimicrobial Stewardship Program (VASP) is seeking to ensure optimum use of antibiotics and other antimicrobial drugs at Vanderbilt University Medical Center (VUMC).

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Bacterial secretion machinery: 3-D view

Dec. 11, 2014—New structural findings reveal how "gatekeeper" proteins participate in the secretion systems bacteria use to infect host cells.

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Antibiotics, fetal vessel defect linked

Oct. 15, 2014—Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis.

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Penicillin equally effective as ‘big gun’ antibiotics for treating less severe childhood pneumonia, Vanderbilt study shows

Dec. 9, 2013—Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with “big gun” antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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