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beta cells Archives

Building a pancreas

Jan. 17, 2019—Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.

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Beta cell biomarker findings may speed diabetes research

Nov. 29, 2018—Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding, reported this month in the journal Cell Metabolism, could lead to improved ways to study and treat diabetes.

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Cellular calcium handling in diabetes

Sep. 28, 2017—Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

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Therapeutic targets for diabetes

May. 3, 2017—Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes.

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Making human beta cells reproduce

Dec. 8, 2016—A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells.

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Fighting type 2 diabetes with FGF1

Nov. 18, 2015—The growth factor FGF1 induces the growth of new insulin-producing beta cells and may help treat type 2 diabetes.

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New therapeutic target for diabetes

Aug. 20, 2015—The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes.

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Boosting beta cells in diabetes

Apr. 20, 2015—New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.

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CaMKII enhances insulin secretion

May. 14, 2014—The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

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Searching for beta cell stimulators

Jan. 13, 2014—Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.

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Pancreas cells full of potential

Feb. 18, 2013—Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.

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Pumping up the pancreas in pregnancy

Jan. 20, 2012—A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.

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Recent Stories from VUMC News and Communications Publications

The first few minutes of Charlie’s life were a blur, as a team of doctors and nurses at VUMC worked to resuscitate him and stabilize his heart rate. He was then transferred to the Neonatal Intensive Care Unit at Monroe Carell Jr. Children’s Hospital at Vanderbilt.

Hope

The first few minutes of Charlie’s life were a blur, as a team of doctors and nurses at VUMC worked to resuscitate him and stabilize his heart rate. He was then transferred to the Neonatal Intensive Care Unit at Monroe Carell Jr. Children’s Hospital at Vanderbilt.

Tucked away in a Vanderbilt conference room, 36 adults huddle over Lego pieces. Eleven teams have been assigned to assemble multicolored Legos using the written directions included in the packet. The result should be a Frankenstein figure.

Vanderbilt Nurse

Tucked away in a Vanderbilt conference room, 36 adults huddle over Lego pieces. Eleven teams have been assigned to assemble multicolored Legos using the written directions included in the packet. The result should be a Frankenstein figure.

Marissa Benchea has CF, and she is one of hundreds of thousands of adults not only surviving but thriving with a chronic childhood disease.

Vanderbilt Medicine

Marissa Benchea has CF, and she is one of hundreds of thousands of adults not only surviving but thriving with a chronic childhood disease.

One hundred years ago, multiple “waves” of a deadly flu swept across the world.

Vanderbilt Medicine

One hundred years ago, multiple “waves” of a deadly flu swept across the world.

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