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cancer biology Archives

Protein loss promotes cell migration

Feb. 28, 2019—The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.

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Breast cancer-killing RIG

Dec. 13, 2018—A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.

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“Idling” cancer cells may return

Apr. 11, 2018—Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment.

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Radiation and pulmonary fibrosis

Nov. 15, 2017—To develop strategies for preventing radiation-induced lung fibrosis (scarring), Vanderbilt investigators are exploring the cell types and factors that contribute to the fibrotic response.

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Boosting sarcoma cell death

Oct. 4, 2017—A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas.

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Special symposium to honor Moses’ cancer research contributions is Oct. 11

Sep. 21, 2017—A research symposium honoring the career of Harold (Hal) Moses, M.D., who founded and served as director emeritus of Vanderbilt-Ingram Cancer Center, has been slated for Wednesday, Oct. 11, 7:45 a.m. – 3:30 p.m., at the Vanderbilt Student Life Center.

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Stress may switch on bone “mets”

Aug. 9, 2017—New findings could explain the link between chronic stress and reduced survival in women diagnosed with breast cancer, and could lead to new strategies to improve treatment outcomes.

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Early drivers of gastric cancer

Aug. 8, 2017—Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers.

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Drivers of breast cancer metastasis

Jul. 20, 2017—Signaling through a complex of proteins called mTORC2 plays a role in breast cancer migration, invasion and metastasis, Vanderbilt researchers reported.

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Vanderbilt’s Christine Lovly elected to American Society for Clinical Investigation

Apr. 24, 2017—  Christine Lovly, M.D., Ph.D., assistant professor of Medicine and Cancer Biology at Vanderbilt University Medical Center (VUMC), has been elected to The American Society for Clinical Investigation (ASCI). The ASCI is an elite honor society of physician-scientists. The Society, founded in 1908, is home to nearly 3,000 members from the upper ranks of academic...

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Blocking neuroblastoma cell growth

Mar. 22, 2017—An inhibitor of cell metabolism may be a good therapeutic target for neuroblastoma, which accounts for about 15 percent of pediatric cancer-related deaths.

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Esophageal cancer complexities

Mar. 16, 2017—New findings that reveal complex interactions in esophageal adenocarcinoma could lead to diagnostic, prognostic or therapeutic biomarkers.

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Recent Stories from VUMC News and Communications Publications

The first few minutes of Charlie’s life were a blur, as a team of doctors and nurses at VUMC worked to resuscitate him and stabilize his heart rate. He was then transferred to the Neonatal Intensive Care Unit at Monroe Carell Jr. Children’s Hospital at Vanderbilt.

Hope

The first few minutes of Charlie’s life were a blur, as a team of doctors and nurses at VUMC worked to resuscitate him and stabilize his heart rate. He was then transferred to the Neonatal Intensive Care Unit at Monroe Carell Jr. Children’s Hospital at Vanderbilt.

Tucked away in a Vanderbilt conference room, 36 adults huddle over Lego pieces. Eleven teams have been assigned to assemble multicolored Legos using the written directions included in the packet. The result should be a Frankenstein figure.

Vanderbilt Nurse

Tucked away in a Vanderbilt conference room, 36 adults huddle over Lego pieces. Eleven teams have been assigned to assemble multicolored Legos using the written directions included in the packet. The result should be a Frankenstein figure.

Marissa Benchea has CF, and she is one of hundreds of thousands of adults not only surviving but thriving with a chronic childhood disease.

Vanderbilt Medicine

Marissa Benchea has CF, and she is one of hundreds of thousands of adults not only surviving but thriving with a chronic childhood disease.

One hundred years ago, multiple “waves” of a deadly flu swept across the world.

Vanderbilt Medicine

One hundred years ago, multiple “waves” of a deadly flu swept across the world.

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