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cholesterol Archives

Obesity negates beneficial drug effects

Nov. 8, 2018—A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.

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Scavengers “protect” HDL

Jun. 29, 2018—Jun. 29, 2018—Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease.

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Oxidative stress on the brain

Aug. 23, 2017—Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders.

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VU team explores new cholesterol processing pathway

Apr. 23, 2015—A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing.

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Kidney disease impacts HDL function

Feb. 11, 2015—Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month.

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Team spots key regulator for cholesterol production

Oct. 2, 2014—A Vanderbilt University-led research team has discovered a “master regulator” for cholesterol production and transport in the liver — a tiny piece of RNA called microRNA-223.

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Major grant spurs deeper look into ‘good cholesterol’

Aug. 21, 2014—In some cases, HDL, the "good cholesterol," may not function properly and may actually accelerate atherosclerosis.

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Antioxidants promising for rare disorder

Feb. 6, 2014—The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development.

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Nobel laureate describes decades-long pursuit of cholesterol regulation

May. 2, 2013—Cholesterol is a tricky molecule to keep in balance. It’s a building block for the cell membrane and is required for cell growth and survival. But too much cholesterol forms solid crystals that are toxic and deadly. In last week’s 2013 Earl W. Sutherland lecture, Nobel laureate Michael Brown, M.D., described his four-decade quest to...

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HDL cholesterol impaired in kidney disease

Jan. 21, 2013—HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

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Genes, nutrients interact to shape traits

Dec. 12, 2012—A new study identifies interactions between genes and nutrients that may participate in determining levels of cholesterol and triglycerides.

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Don’t miss the Love Your Heart Expo Wednesday

Sep. 7, 2012—September is National Cholesterol Education Month and Health Plus is encouraging faculty and staff to get cholesterol checks if recommended, and to take steps to lower cholesterol if it is high. It is also a good time to learn about lifestyle choices that can make a difference. Love Your Heart Expo is a lunchtime event...

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