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Clinical Cancer Research Archives

Study finds breast cancer recurrence score has different implications for men

Nov. 20, 2019—A study published last year offered good news for women with early-stage ER-positive breast cancer who scored at intermediate risk for recurrence. However, a new study finds this conclusion may not directly apply to male patients with the same type of breast cancer

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Study reframes approach to targeted therapy resistance

Apr. 11, 2019—When a tumor mutates and develops resistance to a targeted therapy, researchers often focus on the acquisition of new mutations within the drug target as they seek an alternative treatment, but a team of Vanderbilt scientists has shown this may not be sufficient.

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Improving therapies for GI tumors

Feb. 20, 2017—A signaling protein overexpressed in upper gastrointestinal cancers is an attractive therapeutic target.

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Drug combos for glioblastoma

May. 3, 2016—Vanderbilt researchers have discovered that activation of a certain signaling pathway protects brain cancers from targeted therapies, suggesting that using therapeutics that block both pathways may be a promising treatment.

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Five candidates sought for Runyon Cancer Clinical Investigator Award

Nov. 13, 2015—Vanderbilt University may nominate five candidates for the 2016 Damon Runyon Cancer Research Foundation Clinical Investigator Award.

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PET probe detects dying tumor cells

May. 8, 2014—A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine.

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New drugs a good BET for brain cancer

Mar. 20, 2013—A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors.

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New drug mutes more melanomas

Apr. 26, 2012—An experimental melanoma drug may be beneficial for patients not eligible for targeted therapies.

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Factor sensitizes cancer to radiation

Apr. 6, 2012—Measuring levels of an enzyme in head and neck tumors may indicate how the tumor will respond to radiation therapy.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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