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COX-2 Archives

COX-2 ‘conjugate’ may slow growth of some tumors: study

Jan. 19, 2017—More than a decade after the anti-inflammatory drugs Vioxx and Bextra were pulled from the market because of a heightened risk of heart attack and stroke in some patients, COX-2 inhibitors may be on the verge of a comeback, this time as anti-cancer agents.

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Imaging probe for retinal disease

Oct. 12, 2016—An imaging probe developed at Vanderbilt detects retinal inflammation early and may allow therapeutic intervention to prevent blindness.

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COX-2 blocker could help PTSD

May. 12, 2016—COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression.

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The yin and yang of COX-2

Oct. 2, 2015—New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.

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Lit up COX-2 cancer probe

Jun. 17, 2015—A new imaging probe developed by Vanderbilt investigators enhances tumor visibility and has broad applications in diagnosing and monitoring patients with cancer.

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Low-dose aspirin’s protective effect in cancer explained

Oct. 2, 2014—For years, scientists have known that regular aspirin use may reduce the risk of cancer.

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Vanderbilt scientists discover potential new way to treat anxiety

Aug. 5, 2013—Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural “endocannabinoids” without gastrointestinal side effects, Vanderbilt University scientists will report next week.

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Urine biomarker for colon cancer?

Mar. 10, 2012—A molecule detectable in urine may be helpful in diagnosing colon cancer.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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