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Developmental Cell Archives

Microvilli in motion

Sep. 19, 2019—Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.

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Building a pancreas

Jan. 17, 2019—Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.

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Enzyme helps build motor that drives neuron death

Aug. 23, 2018—Vanderbilt scientists have discovered a signaling mechanism that tells neurons to die, findings that could lead to new treatments for neurodegenerative diseases.

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Building intestinal brush borders

Feb. 8, 2016—Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease.

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Findings offer new insight on how cell division proteins work

Jan. 28, 2016—A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by Vanderbilt researchers.

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Microtubules act as cellular ‘rheostat’ to control insulin secretion

Dec. 3, 2015—Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell.

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VU study reveals factor’s new role in cell division, migration

Oct. 30, 2014—Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.

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VU study points to central regulator of neuron development

Dec. 12, 2013—Developmental biologist Chin Chiang, Ph.D., and his colleagues have discovered that Purkinje neurons in the cerebellum act as central regulators of neuronal development.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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