diabetes

Teams to create one-stop resource for human pancreatic data to foster diabetes research

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health (NIH) to create the world’s first, integrated knowledge base of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.

From left, John Kuriyan, PhD, Vanderbilt Prize recipient Frances Ashcroft, PhD, Vanderbilt Prize Student Scholar Yasminye Pettway, Kathleen Gould, PhD, and Jennifer Pietenpol, PhD. (photo by Donn Jones)

Vanderbilt Prize winner’s lecture focused on the joy of discovery

During her Discovery Lecture on March 21, Professor Dame Frances Ashcroft, recipient of the 2023 Vanderbilt Prize in Biomedical Science, spoke on the joy science has given her.

GRADE Study expands results of major NIH-sponsored comparative study of glucose lowering medications in Type 2 diabetes

The study, which included more than 5,000 volunteers with Type 2 diabetes from diverse racial and ethnic groups, compared the treatments insulin glargine, liraglutide, glimepiride and sitagliptin.

Study links small pancreas size to faster progression to stage 3 Type 1 diabetes

The study findings, published in the journal Diabetes Care, suggest that pancreas imaging can have a benefit in tracking disease development and recruitment for preventive and therapeutic trials.

A biomarker for early Type 2 diabetes

Genetic analyses suggest that branched chain amino acids may be a sensitive biomarker of early or subclinical Type 2 diabetes and could be used to identify risk and implement preventive measures.

Study shows liraglutide results in increased insulin sensitivity independent of weight loss

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