Skip to main content

drug discovery Archives

Channel drug restores glucose balance

Apr. 16, 2014—A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.

Read more


Small molecule protects kidney filter

Mar. 19, 2014—A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier.

Read more


Fishing for new anti-cancer drugs

Sep. 18, 2013—Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug.

Read more


Institute of Chemical Biology to celebrate 10th anniversary

Feb. 28, 2013—Top chemists from around the country will be on hand March 12 to celebrate the 10th anniversary of the Vanderbilt Institute of Chemical Biology (VICB), a brave experiment that helped jumpstart the University’s robust drug discovery initiative.

Read more


Structural snapshot hints at new influenza approach

Feb. 21, 2013—A careful look at how the body’s natural defenses disarm virulent strains of influenza hints at the possibility of a way to fight the flu.

Read more


Insights for neuroscience drug discovery

Jul. 17, 2012—When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects.

Read more


New tool hooks heart failure drugs

Apr. 6, 2012—A new screening tool – using glowing fish embryos – could identify therapeutics for myocardial hypertrophy and heart failure.

Read more


Fishing for heart attack repair tools

Jan. 5, 2012—Managing myocardial infarction – and the resulting heart failure – remains a clinical challenge. To search for chemicals that can stimulate cardiac muscle cell production, Vanderbilt Institute of Chemical Biology investigators led by Tao Zhong, Ph.D., Terri Ni, Ph.D., and Eric Rellinger, M.D., turned to a novel drug discovery tool: zebrafish. The researchers visually screened...

Read more


Drug-like molecules aimed at improving treatment of Parkinson’s

Sep. 30, 2011—Drug-like molecules described by Vanderbilt researchers could lead to Parkinson's treatments with fewer side effects.

Read more


Neuroscience drug discovery center opens at Vanderbilt

Mar. 11, 2011—Vanderbilt University Medical Center has established a new Center for Neuroscience Drug Discovery to accelerate research that may lead to new treatments for Parkinson's disease, schizophrenia and other disorders of the brain.

Read more


Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

more