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drug repurposing Archives

Treating C. diff: new purpose for an old drug?

Sep. 24, 2019—An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.

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Clinical study tests drug that may prevent cancer metastasis

Jul. 8, 2019—A clinical study of a drug that may block cancer metastasis is currently enrolling patients at the Vanderbilt-Ingram Cancer Center.

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VUMC drug repurposing initiative gaining momentum

Apr. 19, 2018—Drug repurposing involves establishing an additional approved indication for a drug already at market.

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Grant bolsters study of potential new therapy for C. diff infection

Mar. 22, 2018—According to the Centers for Disease Control and Prevention, in 2011 in the United States there were almost half a million Clostridium difficile infections, and one in 11 patients 65 or older with a healthcare-associated C. diff infection died within 30 days of diagnosis.

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Study explores anti-viral potential of existing drugs

Sep. 15, 2016—Emerging viral infections like Zika keep popping up around the world in such quick succession that medicine is having a hard time keeping up. It can take 15 years and more than a billion dollars to bring a new drug to market.

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Initiative seeks to bolster ‘rediscovery research’

Sep. 10, 2015—The Vanderbilt Institute for Clinical and Translational Research (VICTR) is partnering with a public charity, Cures Within Reach, to encourage “rediscovery research,” the “repurposing” of already approved medical treatments to other conditions or diseases for which there are no “universally” effective therapies.

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Team finds drug repurposing signal in e-health records

Nov. 20, 2014—With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increasing production.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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