gene mutation Archives
NOTCH1 role in heart development
Jul. 3, 2017—The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.
Mutation raises heart block risk
Mar. 3, 2017—A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care.
Gene mutation discovery may hold autism clues: study
Feb. 2, 2017—Researchers at Vanderbilt have identified what may be a genetic “smoking gun” for autism spectrum disorder (ASD) — a mutation in the gene for the critical neuronal protein CaMKII.
In search of new cancer targets
Sep. 9, 2016—Vanderbilt researchers developed a new algorithm to find clinically targetable gene rearrangements in cancers.
Landmark report urges caution before releasing gene drive-modified organisms
Jun. 9, 2016—A new report released this week raises questions about “gene drives,” a biological process that can profoundly and rapidly alter the characteristics of entire species.
A “CRISPR” way to study disease
Jun. 11, 2015—Using revolutionary CRISPR technology, Vanderbilt investigators have developed a fast and simple method to simultaneously turn off multiple genes in order to study complex diseases.
Genome-editing pioneer next up in Discovery Lecture series
Jan. 2, 2015—Jennifer Doudna, Ph.D., recipient of a 2015 Breakthrough Prize in Life Sciences, will deliver the next Flexner Discovery Lecture on Thursday, Jan. 8.
Schizophrenia ‘switches’ discovered
Sep. 12, 2014—Drugs developed at Vanderbilt could provide a new way to treat schizophrenia in a personalized way.
New technique accelerates genome editing process
Aug. 21, 2014—It sounds like a potato chip. But CRISPR is actually the acronym for a new genome editing technique that, by many accounts, is accelerating the study of genes and disease.
VU study sheds new light on DNA replication
Nov. 7, 2013—David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes.
VU study identifies DNA changes in drug-resistant cancer cells
Sep. 12, 2013—Vanderbilt investigators have combined next-generation sequencing technologies and bioinformatics analyses to screen for genome-wide genetic mutations associated with drug resistance in a series of lung cancer cell lines.
Insights on glaucoma gene mutations
Jun. 26, 2013—Glaucoma-causing mutations in the gene for myocilin reduce secretion of the protein into the aqueous humor, suggesting a new option for treatment.
