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genes Archives

Web tool speeds pulmonary hypertension discovery

Mar. 5, 2014—The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis.

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A pain in the … genes

Jan. 10, 2014—Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception.

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Eye disorder’s genetic risk factors come into focus

Mar. 7, 2013—An international group of investigators has identified seven new genetic regions associated with age-related macular degeneration (AMD), a common cause of blindness in older individuals.

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Gene ‘dose’ may be key to autism

Mar. 4, 2013—Individuals with overexpression of the gene MECP2 have core features of autism spectrum disorder.

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Setting traps to probe gene function

Oct. 18, 2012—A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function.

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Vanderbilt identifies genes linked to breast cancer chemo resistance

Jun. 11, 2012—A study led by Vanderbilt-Ingram Cancer Center investigators has identified a gene expression pattern that may explain why chemotherapy prior to surgery isn’t effective against some tumors and suggests new therapy options for patients with specific subtypes of breast cancer.

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Worm gene function? Check the map.

Mar. 3, 2011—New gene expression atlas created for roundworms provides a basis for establishing roles for individual genes in the development of specific cell types.

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Fluorine aids gene silencing

Feb. 15, 2011—Modifying a form of RNAs may improve their efficacy for research and medical uses.

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Gene variant doubles risk of developing autism

Jan. 1, 2008—A Vanderbilt research team reports, in the largest study of any single gene, that a gene, identified in cancer, is also involved in autism.

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