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GWAS Archives

Connecting an asthma gene to leukemia

Aug. 2, 2018—A receptor previously implicated in asthma may also play roles in other allergic diseases and in leukemia, Vanderbilt researchers have discovered.

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Vanderbilt study links gene expression, disease association data

Jul. 26, 2018—An international team of researchers has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases.

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Shared genetics may shape treatment options for certain brain disorders

Jun. 14, 2018—Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting.

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Probing the genetics of autoimmunity

Jul. 21, 2017—Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets.

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Genetics of lung cancer survival

Jun. 29, 2017—Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans.

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VU study reveals shared pathways in psychiatric disorders

Sep. 18, 2014—Schizophrenia and bipolar disorder share common genetic underpinnings. Vanderbilt researchers combined high-resolution gene expression studies with gene association data to reveal signaling pathways linked to schizophrenia and bipolar disorder.

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Pioneers of Discovery: Computer science drives Capra’s biomedical research

Oct. 3, 2013—Tony Capra, Ph.D., is a new assistant professor of Biomedical Informatics and investigator in the Center for Human Genetics Research at Vanderbilt. His goal is to use the tools of computer science to address problems in genetics, evolution and biomedicine.

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Gene interactions and cavities

Sep. 30, 2013—Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay.

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Tool finds connections in genome data

Feb. 8, 2012—A new analytical tool points to genes that act together to increase disease risk.

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Study applies random genotype sets to new disease

Jan. 5, 2012—A new study in the American Journal of Human Genetics, led by Vanderbilt researchers Josh Denny, M.D., M.S., and Dana Crawford, Ph.D., takes random volumes of human genotypes and matches them with data siphoned from de-identified medical records and sheds new light on the genetic basis of the common disease hypothyroidism. In a research lab,...

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