Skip to main content

inflammatory bowel disease Archives

Host-microbe interactions in the gut

Aug. 13, 2019—Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.

Read more


Intestinal immune cell interactions

Jul. 30, 2019—Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

Read more


Lighting up colorectal cancer

Feb. 28, 2019—A nanobeacon imaging agent that binds specifically to colorectal cancer cells may aid the early detection of cancer during colonoscopy.

Read more


Novel insights on “leaky” gut

Jul. 19, 2018—A protein involved in binding cells together helps maintain the integrity of the intestinal mucosa and plays a protective role in ulcerative colitis.

Read more


Lineage tracing in the gut

Nov. 30, 2017—Vanderbilt investigators have developed an algorithm to classify cell types from experimental data, making it possible to understand how organs develop.

Read more


Gut response to fluid flow

Oct. 26, 2017—Vanderbilt researchers have discovered that microvilli – finger-like projections from cells in the intestine – respond to the shear stress of fluid flow to drive a cellular pathway that regulates nutrient balance.

Read more


EGF receptor found to regulate macrophage inflammation in gut

Oct. 13, 2016—Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract.

Read more


Study explores protein’s role in inflammation-associated cancer

Jul. 23, 2015—An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

Read more


Increased cell permeability may protect from colitis

Apr. 25, 2014—Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.

Read more


Target for inflammatory bowel disease

Mar. 1, 2013—The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.

Read more


Plant compound quells inflammation

Apr. 6, 2012—Berberine, an herbal remedy for diarrhea and intestinal parasites, may be an effective treatment for gastrointestinal inflammatory diseases.

Read more


Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

more