Skip to main content

Molecular Physiology & Biophysics Archives

Altered dopamine signaling may offer a clue to autism

Jan. 29, 2015—Newly discovered genetic variations linked to autism spectrum disorder (ASD) disrupt the function of the dopamine transporter, suggesting that altered dopamine signaling contributes to this common developmental condition, according to a Vanderbilt University-led research team.

Read more


New signaling pathway provides clues to obesity

Jan. 22, 2015—A Vanderbilt University-led research team has discovered a molecular “rheostat” in the brain’s appetite control center that may provide new insights into obesity, which is at epidemic levels in this country.

Read more


Neuert receives New Innovator Award from NIH

Oct. 9, 2014—Vanderbilt University biophysicist Gregor Neuert, Ph.D., M.Eng., is among 50 recipients of the 2014 National Institutes of Health (NIH) Director’s New Innovator Award. Each award provides up to $1.5 million in direct research support over five years.

Read more


Team spots key regulator for cholesterol production

Oct. 2, 2014—A Vanderbilt University-led research team has discovered a “master regulator” for cholesterol production and transport in the liver — a tiny piece of RNA called microRNA-223.

Read more


Team takes 4-D look at brain receptor’s role

Aug. 14, 2014—Reporting last week in the journal Cell, researchers from Oregon Health and Science University, Harvard Medical School and Vanderbilt University describe the first “four-dimensional” picture of a brain receptor that plays a key role in learning and memory.

Read more


Vanderbilt study supports notion ‘You are what you eat’

Jun. 2, 2014—An international research group led by Vanderbilt University scientists has shown for the first time that a lipid, or fat molecule, can regulate “psychostimulant” behaviors by interacting with a brain protein.

Read more


CaMKII enhances insulin secretion

May. 14, 2014—The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

Read more


Relaxin combats insulin resistance

Oct. 16, 2013—The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance.

Read more


Intracellular receptor expert set for next Discovery Lecture

Oct. 3, 2013—Keith Yamamoto, Ph.D., an international leader in the study of signaling and gene regulation by intracellular receptors, will deliver the next Flexner Discovery Lecture on Thursday, Oct. 10.

Read more


Disease linked to cell traffic jams

Jun. 20, 2013—Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface.

Read more


Food variety drives overeating in mouse model of obesity syndrome

Apr. 25, 2013—Dietary variety – not high-fat or sugary foods – appears to stimulate overeating in a mouse model of an inherited obesity syndrome.

Read more


UT Southwestern’s Brown set to deliver Flexner Discovery Lecture

Apr. 18, 2013—Nobel laureate Michael Brown, M.D., whose research paved the way for the development of cholesterol-lowering statin drugs, will deliver the next Flexner Discovery Lecture on Thursday, April 25.

Read more


Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

more