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Mouse Metabolic Phenotyping Center Archives

Bile acids mediate metabolic benefits of weight-loss surgery

Jan. 10, 2019—A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery.

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Insulin accelerant

Oct. 11, 2018—It’s possible to increase the permeability of blood vessels and accelerate insulin action in muscle, Vanderbilt researchers have discovered.

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Voluntary exercise and energy balance

Mar. 23, 2018—Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered.

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Phenotyping center a global resource for investigators

Nov. 16, 2017—This summer the Vanderbilt Mouse Metabolic Phenotyping Center (MMPC) began its 17th year of continuous operation and federal support with a $5.5 million, five-year renewal grant from the National Institutes of Health (NIH).

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Study spots possible new approach to prevent obesity

Apr. 14, 2016—An international research team that included scientists from Vanderbilt University Medical Center has found a novel way to counteract obesity in mice — by stimulating the growth of blood vessels in fat tissue.

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Photo: Mouse Metabolic Phenotyping Center

Jun. 25, 2015—David Wasserman, Ph.D., kicks off Wednesday’s ribbon cutting and open house to celebrate the newly renovated Mouse Metabolic Phenotyping Center (MMPC) on the eighth floor of Light Hall. The center, founded in 2001, provides novel techniques for studying mouse models of diabetes and other metabolic disorders. As measured by the scientific papers that flow out...

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VUMC research cores speed pace of discovery

Jan. 22, 2015—Progress against America’s most intractable health challenges, among them heart disease, cancer and diabetes, requires the best minds, the latest tools and the easy collaboration demanded by 21st century science.

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Matrix remodeling and insulin resistance

Apr. 10, 2014—The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

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Relaxin combats insulin resistance

Oct. 16, 2013—The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance.

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Matrix member key to insulin resistance

Jun. 6, 2013—A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.

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