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myelin Archives

Discovery sheds light on protein key to nerve cells’ myelin sheath

Aug. 17, 2017—Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear.

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Myelin repair factors

Apr. 19, 2016—Vanderbilt researchers show that two factors promote the repair of myelin, the nerve cell covering that deteriorates in diseases such as multiple sclerosis.

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Using MRI to assess myelin health

Jan. 25, 2016—Vanderbilt investigators report an improved model for estimating brain health, using MRI.

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RNA defects in multiple sclerosis

Apr. 30, 2015—Vanderbilt researchers have discovered that profound defects exist in the integrity of structural RNA molecules in patients with relapsing remitting multiple sclerosis.

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Myelin junctions key to conduction

Apr. 11, 2014—A protein in the myelin coating on nerves helps form a “seal” that enables effective nerve conduction; loss of the protein causes inherited neuropathies.

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Early cell death in MS

Oct. 2, 2013—Death of oligodendrocytes, the cells that make myelin, appears to be an early event in the development of multiple sclerosis.

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Methods for imaging myelin loss

Jul. 12, 2013—Certain MRI metrics can be used to assess myelin loss in multiple sclerosis, which is important for planning and monitoring therapy.

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Recent Stories from VUMC News and Communications Publications

Marissa Benchea has CF, and she is one of hundreds of thousands of adults not only surviving but thriving with a chronic childhood disease.

Vanderbilt Medicine

Marissa Benchea has CF, and she is one of hundreds of thousands of adults not only surviving but thriving with a chronic childhood disease.

One hundred years ago, multiple “waves” of a deadly flu swept across the world.

Vanderbilt Medicine

One hundred years ago, multiple “waves” of a deadly flu swept across the world.

A diagnosis of cancer at any age is tragic, but during the adolescent and young adult years, it’s especially complicated.

Hope

A diagnosis of cancer at any age is tragic, but during the adolescent and young adult years, it’s especially complicated.

Karen Dyer Young cares for patients and members of the Dayani Center who have or are recovering from cancer or a stem cell transplant.

Momentum

Karen Dyer Young cares for patients and members of the Dayani Center who have or are recovering from cancer or a stem cell transplant.

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