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Nature Medicine Archives

Encephalitis identified as rare toxicity of immunotherapy treatment

Jul. 22, 2019—Researchers are chronicling rare but serious toxicities that may occur with immune checkpoint inhibitors, the most widely prescribed class of immunotherapies.

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Genetic characteristics of peripheral artery disease studied

Jul. 18, 2019—New study explores why some people with peripheral artery disease present with problems with their legs, some with their heart and some with strokes.

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Team’s findings could spur new treatments for type 2 diabetes

Sep. 6, 2018—An international research team including scientists from Vanderbilt University has discovered how the diabetes drug metformin blocks glucose production by the liver. The discovery, reported Aug. 27 in the journal Nature Medicine, could lead to development of new ways to treat type 2 diabetes.

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VUMC researchers find a way to ‘starve’ cancer

Jan. 16, 2018—Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital nutrient glutamine.

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Researchers find novel mechanism of resistance to anti-cancer drugs

Oct. 17, 2017—Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

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Study shows excess dietary zinc worsens C. diff infection

Sep. 26, 2016—Too much dietary zinc increases susceptibility to infection by Clostridium difficile — “C. diff” — the most common cause of hospital-acquired infections.

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Lung cancer study reveals new drug combination targets

Sep. 4, 2014—A Vanderbilt lung cancer patient’s exceptional response to different types of therapies spurred research that suggests lung cancer patients with specific gene alterations may benefit from combination therapy that targets two different cancer pathways.

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Novel treatment strengthens bones in genetic disease

Aug. 7, 2014—An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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