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Nature Archives

Study identifies critical regulator of tumor-specific T cell differentiation

Jun. 18, 2019—A study published June 17 in Nature offers clues as to why blocking inhibitory receptors on tumor-infiltrating T cells may not always work

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Researchers push forward frontiers of vaccine science

Feb. 13, 2019—Using sophisticated gene sequencing and computing techniques, researchers at Vanderbilt University Medical Center and the San Diego Supercomputer Center have achieved a first-of-its-kind glimpse into how the body’s immune system gears up to fight off infection.

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Alphavirus “Achilles heel”

May. 17, 2018—Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses.

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Study catches ‘notorious’ drug pump in action

Mar. 16, 2017—Researchers at Vanderbilt University Medical Center (VUMC) have mapped the conformational changes that occur in a protein “notorious” for pumping chemotherapeutic drugs out of cancer cells and blocking medications from reaching the central nervous system.

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Early study finds antibody that ‘neutralizes’ Zika virus

Nov. 7, 2016—Researchers at Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis have isolated a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus.

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Study explores low oxygen’s impact on antibody quality

Aug. 11, 2016—Hypoxia (lack of enough oxygen) is bad for the body as a whole, but in the neighborhood where infection-fighting antibodies arise, may be important for keeping proper order.

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New signaling pathway provides clues to obesity

Jan. 22, 2015—A Vanderbilt University-led research team has discovered a molecular “rheostat” in the brain’s appetite control center that may provide new insights into obesity, which is at epidemic levels in this country.

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Colon cancer’s protein signatures identified

Jul. 24, 2014—A Vanderbilt University-led research team has identified protein “signatures” of genetic mutations that drive colorectal cancer, the nation’s second leading cause of cancer deaths after lung cancer.

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Study finds ‘hot’ frogs fight off fungal pathogen

Jul. 9, 2014—Simple heat treatments may give the frog immune system a boost and help it fight off a deadly fungal pathogen, according to a new study published July 10 in the journal Nature.

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Investigators seek clues to resistance to melanoma drug

Jan. 26, 2012—Investigators at Vanderbilt-Ingram Cancer Center and several other centers may be one step closer to finding out why some melanoma patients relapse after treatment with a promising new drug.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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