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NCI Archives

Novel insights on “leaky” gut

Jul. 19, 2018—A protein involved in binding cells together helps maintain the integrity of the intestinal mucosa and plays a protective role in ulcerative colitis.

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New player in DNA damage repair

Jul. 19, 2018—New findings open opportunities to understand mechanisms of DNA repair for a toxic form of DNA damage.

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SMAD4 clue to colon cancer

Jul. 2, 2018—Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers.

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Confronting TB resistance

Jun. 11, 2018—Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis.

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$8.1 million grant funds new center to research highly aggressive form of lung cancer

Jun. 8, 2018—A five-year National Cancer Institute grant will fund an interdisciplinary research center for the study of small cell lung cancer, a highly aggressive, incurable form of the disease.

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New breast cancer targets

May. 4, 2018—A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer.

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Toxin floats on lipid rafts

Apr. 23, 2018—The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells.

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Disease-fighting antibody production

Apr. 20, 2018—New research links nutrient-responsive cellular signaling to the antibody-mediated immune response.

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How the skin protects

Apr. 19, 2018—Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier.

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“Idling” cancer cells may return

Apr. 11, 2018—Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment.

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Mitochondrial mutations and disease

Feb. 22, 2018—New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state.

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A spicy finding

Jan. 16, 2018—Vanderbilt researchers have discovered that curcumin — the active ingredient in the spice turmeric — needs to be metabolically activated to exert anti-inflammatory effects.

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