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New England Journal of Medicine Archives

Combination therapy improves small-cell lung cancer survival

Oct. 25, 2018—Patients with stage IV small-cell lung cancer lived longer when given the immunotherapy atezolizumab with chemotherapy, setting the stage for what could become the first new treatment approved in decades for this particularly aggressive form of lung cancer.

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Antipsychotics ineffective for treating ICU delirium: study

Oct. 22, 2018—Critically ill patients are not benefiting from antipsychotic medications that have been used to treat delirium in intensive care units (ICUs) for more than four decades, according to a study released today in the New England Journal of Medicine.

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Time window extended for some stroke surgeries

Mar. 1, 2018—New research indicates the time window for a thrombectomy following a stroke is longer than previously thought, but how soon the surgery occurs still matters.

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Saline use on decline at Vanderbilt following landmark studies

Feb. 27, 2018—Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released Feb. 27 that are anticipated to improve survival and decrease kidney complications.

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Team finds stem cell transplant improves scleroderma survival

Feb. 15, 2018—A new clinical trial by investigators at Vanderbilt University Medical Center (VUMC) and other leading medical centers found that an intensive transplant treatment using the patient’s own stem cells can improve survival and quality of life for patients with advanced scleroderma.

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NEJM Catalyst forum addresses mental, behavioral and social health determinants

Jan. 29, 2018—Healthcare is more than diagnosing and treating disease. To truly improve health outcomes for individuals and communities, the mental, behavioral and social determinants of health must be fully integrated with physical factors at all levels of the healthcare system.

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New lab formulary improves quality, cuts cost

Sep. 21, 2017—An effort at Vanderbilt University Medical Center (VUMC) to enhance clinical decision making through cross-departmental collaboration and effective use of diagnostics has improved patient care and saved the institution more than $1 million in 2016, VUMC officials reported this week.

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New approach for staph-related skin abscesses explored

Jul. 13, 2017—New multicenter research that includes Vanderbilt University Medical Center (VUMC) investigators, could change treatment approaches to simple skin abscesses, infections often caused by Staphylococcus aureus (staph) bacteria.

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Preserving NIH’s Fogarty International Center crucial for global health efforts

May. 26, 2017—This week Douglas Heimburger, M.D., M.S., professor of Medicine at Vanderbilt, joined a growing chorus calling for preservation of the Fogarty International Center of the National Institutes of Health (NIH).

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Social risk factors influence outcomes, Medicare payment

Feb. 8, 2017—Social risk factors including income, education and ethnic background influence health outcomes and should be taken into account in Medicare payment models, according to a New England Journal of Medicine “Perspective” titled “Social Risk Factors and Equity in Medicare Payment.”

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Study finds smaller insurers earning profits in new market

Feb. 2, 2017—The researchers examine whether the financial struggles of some major insurers under the Affordable Care Act reflect a policy failure or a mismatch of these firms’ capabilities and strategies to a newly created market.

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Automation speeds clinical safety surveillance: study

Jan. 26, 2017—Using patient outcomes data from approximately 1,800 hospitals, the largest demonstration to date of automated safety surveillance of a medical device is reported in this week’s New England Journal of Medicine.

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