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NHLBI Archives

Web tool speeds pulmonary hypertension discovery

Mar. 5, 2014—The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis.

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Probing the pathogenesis of leukemia

Feb. 27, 2014—A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia.

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Keeping the beat after heart surgery

Feb. 10, 2014—Variation in the gene for the beta-1 adrenergic receptor increases the risk that a patient will have an abnormal heart rhythm after cardiac surgery.

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What makes us human?

Nov. 22, 2013—Using computational tools to search for the genetic basis of what makes us human, Vanderbilt Assistant Professor of Biomedical Informatics Tony Capra and colleagues at the University of California-San Francisco have identified promising candidate regions.

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Shining a light on night blindness

Oct. 24, 2013—Vanderbilt researchers are studying how mutations in the receptor for light, rhodopsin, cause light blindness.

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New target for stopping inflammation

Oct. 11, 2013—Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.

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Fishing for new anti-cancer drugs

Sep. 18, 2013—Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug.

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Probing intestinal immune cell roles

Aug. 28, 2013—A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.

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‘Yo-yo dieting’ inflames fat tissue

Aug. 9, 2013—Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

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Nuclear shield against cell death

Aug. 8, 2013—The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

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Reducing fatal rhythms after heart attack

Jul. 26, 2013—Reducing heart muscle response to calcium could decrease the risk of fatal arrhythmias after heart attacks.

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Probing roles of a cell death protein

Jul. 17, 2013—Vanderbilt researchers have discovered new roles for a protein involved in cell death processes that are activated to prevent tumor-causing DNA mutations.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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