Skip to main content

NIEHS Archives

Team’s study reveals details of new DNA repair pathway

Jul. 25, 2019—Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.

Read more


Steroid binding to metabolic enzyme

Jun. 12, 2019—Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.

Read more


The yin and yang of cell signaling

Feb. 14, 2019—Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

Read more


How the skin protects

Apr. 19, 2018—Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier.

Read more


DNA damage repair: molecular insights

Dec. 5, 2017—Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.

Read more


Oxidative stress in tumors

May. 18, 2017—Vanderbilt investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development.

Read more


A new mode of DNA repair

Apr. 14, 2017—Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

Read more


Blood-brain barrier on a chip sheds new light on “silent killer”

Dec. 6, 2016—A new microfluidic device containing human cells that faithfully mimics the behavior of the blood-brain barrier is providing new insights into brain inflammation, the silent killer.

Read more


Study finds natural compound extends lifespan of worms

Oct. 20, 2016—A compound found in buckwheat seeds extends the lifespan of worms, Vanderbilt investigators have discovered.

Read more


Faulty building blocks in DNA

Jan. 22, 2016—An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations.

Read more


How the cell makes morphine

Aug. 25, 2015—Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine.

Read more


Study explores protein’s role in inflammation-associated cancer

Jul. 23, 2015—An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

Read more


Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

more