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NIH Archives

Exploring the brain’s white matter

Mar. 14, 2019—New comprehensive functional MRI measurements point to the need to update models for assessing brain white matter activity and physiology.

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Reprogramming cells for kidney repair

Mar. 14, 2019—Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.

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Lighting up colorectal cancer

Feb. 28, 2019—A nanobeacon imaging agent that binds specifically to colorectal cancer cells may aid the early detection of cancer during colonoscopy.

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Achilles’ heel for kidney cancer

Feb. 28, 2019—The discovery that kidney cells with mutations in a certain gene are sensitive to therapies called PI3K inhibitors opens new opportunities for applying precision medicine to cancer treatment.

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Personalized pain management

Feb. 28, 2019—Understanding how natural brain chemicals with pain-relieving properties interact with administered opioids may guide personalized approaches for pain management.

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Protein loss promotes cell migration

Feb. 28, 2019—The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.

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Novel DNA repair mechanism preserves genome integrity: study

Feb. 28, 2019—Biochemistry investigators at Vanderbilt have discovered a new DNA repair mechanism that prevents gene mutations during DNA replication.

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Discovery points to new cancer immunotherapy option

Feb. 21, 2019—An international team involving Vanderbilt researchers has discovered that a new “checkpoint” protein on immune system cells is active in tumors, and that blocking it — in combination with other treatments — is a successful therapeutic approach in mouse models of cancer.

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Probing H. pylori cancer protein

Feb. 14, 2019—Understanding how a bacterial protein that influences the risk of stomach cancer is produced could guide new strategies for treatment.

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The yin and yang of cell signaling

Feb. 14, 2019—Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

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Modulating stress circuits

Feb. 14, 2019—Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.

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Adhesion protein optimizes border

Feb. 14, 2019—Matthew Tyska and colleagues have found that an adhesion protein plays a key role in building the intestinal brush border that is essential for absorbing nutrients.

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Recent Stories from VUMC News and Communications Publications

Marissa Benchea has CF, and she is one of hundreds of thousands of adults not only surviving but thriving with a chronic childhood disease.

Vanderbilt Medicine

Marissa Benchea has CF, and she is one of hundreds of thousands of adults not only surviving but thriving with a chronic childhood disease.

One hundred years ago, multiple “waves” of a deadly flu swept across the world.

Vanderbilt Medicine

One hundred years ago, multiple “waves” of a deadly flu swept across the world.

A diagnosis of cancer at any age is tragic, but during the adolescent and young adult years, it’s especially complicated.

Hope

A diagnosis of cancer at any age is tragic, but during the adolescent and young adult years, it’s especially complicated.

Karen Dyer Young cares for patients and members of the Dayani Center who have or are recovering from cancer or a stem cell transplant.

Momentum

Karen Dyer Young cares for patients and members of the Dayani Center who have or are recovering from cancer or a stem cell transplant.

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