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NINDS Archives

Vitamin C protects brain from seizures

Nov. 8, 2018—Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.

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Probing the pathology of impaired cognition

Oct. 25, 2018—Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.

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A brain-builder called “Shh”

Aug. 30, 2018—New findings demonstrate a previously unappreciated role of Shh signaling activity in the proliferation of CGNPs — the presumed cell-of-origin for a subset of the malignant pediatric brain tumor medulloblastoma.

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Parkinson’s study to track impact of DBS on earliest patients

Aug. 30, 2018—A decade after taking part in the first clinical trial of deep brain stimulation (DBS) administered during very early-stage Parkinson’s disease, participants will return to Vanderbilt University Medical Center this year to be re-evaluated.

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New view of the heartbeat

Apr. 6, 2018—Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias.

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Long QT syndrome – revealed

Mar. 12, 2018—Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.

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BOLD view of white matter

Jan. 12, 2018—Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis.

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Impulsivity in Parkinson’s Disease

Oct. 27, 2017—A noninvasive MRI technique may help predict a troubling side effect of common medications for Parkinson’s Disease and improve clinical treatment plans.

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Heat a trigger for seizures

Sep. 6, 2017—Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation.

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Predicting brain surgery outcomes

Aug. 18, 2017—Assessing brain functional and structural connectivity in patients with temporal lobe epilepsy may be a useful way to identify the best candidates for surgical treatment.

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Protein structure and epilepsy severity

Nov. 10, 2016—Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy.

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Culprits in genetic epilepsies

Oct. 11, 2016—Genetic variation in GABA-A receptors confers risk for inherited forms of epilepsy.

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