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Scientific Reports Archives

NSAIDs, genetics and miscarriage

Sep. 20, 2017—A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

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Acid reflux cancer link

Sep. 14, 2017—Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.

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Esophageal cancer complexities

Mar. 16, 2017—New findings that reveal complex interactions in esophageal adenocarcinoma could lead to diagnostic, prognostic or therapeutic biomarkers.

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Melanoma study finds new way to enhance targeted therapies

Mar. 9, 2017—With the help of a drug formerly used to treat HIV/AIDS, researchers at Vanderbilt University Medical Center (VUMC) have found a way to make melanoma cells more vulnerable to targeted anti-cancer therapy.

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Improving vaccine formulations

Jan. 20, 2017—The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response.

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Investigators explore new way to control mosquitoes

Dec. 1, 2016—In a new study, Vanderbilt pharmacologist Jerod Denton, Ph.D., Ohio State entomologist Peter Piermarini, Ph.D., and colleagues report an experimental molecule that inhibits kidney function in mosquitoes and thus might provide a new way to control the deadliest animal on Earth.

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Protein structure and epilepsy severity

Nov. 10, 2016—Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy.

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Pulmonary fibrosis culprits

Jun. 6, 2016—New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease.

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New targets for diabetic retinopathy

Jan. 21, 2016—Certain protein factors have been identified as attractive targets for treating diabetic retinopathy, a major cause of blindness in adults.

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‘Stretched’ cells promote cancer

Feb. 19, 2015—Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.

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New tools to probe manganese biology

Nov. 26, 2014—Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

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Recent Stories from VUMC News and Communications Publications

Brighter days ahead

Vanderbilt Medicine

Brighter days ahead

Community care

Vanderbilt Nurse

Community care

Survive and thrive

Hope

Survive and thrive

Combating cancer disparities is an out-of-office assignment

Momentum

Combating cancer disparities is an out-of-office assignment

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