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type 2 diabetes Archives

Diabetes drug may prevent cancer

Sep. 14, 2018—The research suggests that metformin should be further studied clinically for the prevention of liver cancer.

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Team’s findings could spur new treatments for type 2 diabetes

Sep. 6, 2018—An international research team including scientists from Vanderbilt University has discovered how the diabetes drug metformin blocks glucose production by the liver. The discovery, reported Aug. 27 in the journal Nature Medicine, could lead to development of new ways to treat type 2 diabetes.

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Team explores diabetes drug’s ability to treat RSV infection

Jul. 12, 2018—A drug used to treat diabetes may point to new therapies for respiratory syncytial virus (RSV) bronchiolitis — inflammation and obstruction of the lungs’ small airways. A multi-disciplinary team of Vanderbilt investigators has demonstrated that liraglutide reduces the inflammatory response to RSV infection in a mouse model of the disease.

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Study may point to new ways to reverse insulin resistance

Jan. 25, 2018—Researchers at Vanderbilt University have discovered how insulin crosses the capillary endothelium to exit blood vessels and stimulate skeletal muscle cells — a major finding that may lead to new ways to reverse insulin resistance, a hallmark of type 2 diabetes.

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Vanderbilt Pre-Diabetes Clinic tackles type 2 diabetes in children

Jun. 22, 2017—In Middle Tennessee, where roughly one-third of children are overweight or obese, the risk of developing pediatric type 2 diabetes is high and the consequences can be serious.

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Therapeutic targets for diabetes

May. 3, 2017—Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes.

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Diabetes management and low income

Apr. 6, 2016—Adherence to medication was the only self-care activity independently associated with glycemic control in a low-income population.

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Fighting type 2 diabetes with FGF1

Nov. 18, 2015—The growth factor FGF1 induces the growth of new insulin-producing beta cells and may help treat type 2 diabetes.

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Lymphocyte study reveals obesity clues

Oct. 16, 2014—Vanderbilt University researchers are closer to understanding the link between obesity, chronic inflammation and type 2 diabetes.

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Study tracks insulin’s risks as second-line diabetes medication

Jun. 12, 2014—In an observational study by researchers at Vanderbilt University Medical Center, adults with type 2 diabetes who take insulin in addition to the recommended first-line drug therapy, metformin, had a 30 percent higher risk of heart attack, stroke or death when compared to similar patients who instead augment their metformin regimen with a sulfonylurea.

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Matrix remodeling and insulin resistance

Apr. 10, 2014—The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

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Bariatric surgery’s metabolic impact to be explored

Dec. 19, 2013—Vanderbilt University researchers have received a two-year, $1.2 million grant from the National Institutes of Health (NIH) to study a mouse model of the metabolic and hormonal changes caused by bariatric surgery.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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