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Wnt signaling Archives

A “rheostat” for cancer signals

Aug. 27, 2019—Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells.

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Lung diseases share molecular signature

Apr. 5, 2018—Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention.

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Structure of a stem cell niche

Feb. 28, 2018—Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies.

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A target to heal tiny lungs

Feb. 23, 2017—The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth.

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Colorectal cancer clues

Jan. 19, 2017—Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways.

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Wound-healing scaffolds

Jan. 27, 2016—The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring.

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Healing without scarring

Oct. 16, 2015—Drugs that inhibit the Wnt signaling pathway can regenerate injured skin and may be useful in treating fibromatosis, degenerative joint disease and cancer.

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Heart repair factor

Sep. 17, 2015—A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack.

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Therapeutic target for synovial sarcoma

Nov. 21, 2013—Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer.

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Fishing for new anti-cancer drugs

Sep. 18, 2013—Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug.

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Long live the therapeutic stem cells

May. 17, 2012—Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help.

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Colon cancer’s cellular crossroads

Mar. 16, 2012—New information about signaling pathways involved in colorectal cancer could aid in assessing prognosis and identifying new therapeutic targets for the disease.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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