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Research

Study links genetic variants, protein expression and human diseases

Oct. 21, 2021—  by Leigh MacMillan An international research team has connected genetic information and data on thousands of proteins circulating in the blood to develop a gene-protein-disease atlas. The new resource, reported Oct. 14 in the journal Science, shows how genetic variants that regulate protein expression may underlie both related and diverse human diseases. “This study...

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Combo therapy slows prostate cancer

Oct. 19, 2021—A new combination treatment showed promise in slowing the growth of castration-resistant prostate cancer in animal models, Vanderbilt researchers discovered.

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Berlin Institute of Health’s Eils set for next Discovery Lecture

Oct. 18, 2021—Roland Eils, PhD, will discuss efforts to translate the deluge of genomics data generated by international initiatives into understanding disease mechanisms during the next web-based Discovery Lecture.

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Mental health screening in epilepsy

Oct. 18, 2021—Sending survey tools to epilepsy patients before their clinic appointment doubled the numbers of patients who were diagnosed and treated for depression and anxiety disorders, Vanderbilt neurologists found.

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Tea drinking and high blood pressure

Oct. 14, 2021—Habitual tea drinking is associated with a slightly higher risk of hypertension in middle-aged and older Chinese adults, which warrants confirmation by long-term intervention studies, researchers say.

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New marker for metaplasia

Oct. 14, 2021—A protein that transports water, called aquaporin 5, is expressed by cells undergoing changes that may increase risk for gastric cancer development, Vanderbilt researchers discovered.

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Amphibians offer clues to climate change resiliency

Oct. 7, 2021—  by Bill Snyder Like the “canary in the coal mine,” the worldwide decline of amphibian populations, including frogs, toads and salamanders, during the past 50 years may be a harbinger of emerging infections and environmental changes that endanger humankind, as well. Just as important, some amphibian species have begun to recover from the global...

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Nominations sought for VUSM Research Staff Awards

Oct. 7, 2021—  by Bill Snyder Nominations are being accepted for the 2021 Vanderbilt University School of Medicine Research Staff Awards. The awards honor research staff members who provide exemplary support at all levels to the Research Enterprise. Award recipients will receive a $1,000 cash prize and will be honored at an awards luncheon. The following awards are...

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Breaking bad with Huntington’s disease

Oct. 5, 2021—Illegal activities are a significant clinical problem in individuals with Huntington’s disease, highlighting the need for improved screening measures and protocols to guide patient management.

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Neurologic complications of the flu

Oct. 4, 2021—Neurologic complications are common in children hospitalized with influenza, especially those with chronic neurologic conditions, and are associated with worse outcomes.

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VUMC research contributed to first COVID-19 pill now under review

Oct. 1, 2021—Vanderbilt research helped allow pharmaceutical giant Merck & Co. to authorization for the first oral antiviral pill to treat COVID-19.

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Molecular imaging of C. diff infection

Sep. 30, 2021—C. difficile — the leading cause of hospital-associated intestinal infections — induces a rapid influx of bile acids into the gut, which could provide a novel target for blocking infection.

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