VUMC Reporter

Research

VUMC’s Wilkins lands major national award for women physicians

Jul. 23, 2021—Consuelo Wilkins, MD, MSCI, a leader in health equity, diversity and inclusion at Vanderbilt University Medical Center (VUMC), is the 2021 recipient of the Marion Spencer Fay Award from Drexel University College of Medicine in Philadelphia.

Madison Adolph, PhD, left, David Cortez, PhD, and Archana Krishnamoorthy are studying fundamental processes involved in DNA replication.

Researchers discover that protein switches functions to regulate DNA replication

Jul. 22, 2021—Vanderbilt biochemists have discovered what the DNA damage response protein RADX does — and how it does it.

From left, Dan Roden, MD, Ayesha Muhammad, Jonathan Mosley, MD, PhD, and Sara Van Driest, MD, PhD, found that a genome-wide approach can improve the prediction of drug responses.

For more precise drug treatments, ‘squeeze’ the genome: study finds

Jul. 22, 2021—Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center.

Influenza network sizes up COVID

Jul. 22, 2021—Hospital data from a CDC network that monitors influenza revealed that adults hospitalized for COVID-19 in the early months of the pandemic were 20x more likely to die compared to hospitalized influenza patients.

Study identifies monoclonal antibodies that may neutralize many norovirus variants

Jul. 16, 2021—Researchers at Vanderbilt University Medical Center (VUMC) and the Baylor College of Medicine in Houston, Texas, have taken a big step toward developing targeted treatments and vaccines against a family of viruses that attacks the gastrointestinal tract.

Establishing HIV care in Tennessee

Jul. 13, 2021—Vanderbilt researchers find that heterosexually active Black males are the least likely to establish HIV care within one month of diagnosis and suggest that targeted interventions focus on this population.

Probing statin-associated diseases with genetics

Jul. 12, 2021—Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

From left, MacRae Linton, MD, Huan Tao, MD, PhD, Jonathan Brown, MD, and colleagues have discovered a potential new target for preventing atherosclerosis.

Nature’s “recycler” could reduce heart disease risk: study

Jul. 8, 2021—Researchers at Vanderbilt University Medical Center have identified potential new targets for the prevention of atherosclerosis through the enhancement of autophagy, a natural process for recycling damaged cellular material.

Study finds genetic risk factors for severe COVID-19 illness

Jul. 8, 2021—A massive worldwide collaboration including researchers from Vanderbilt University Medical Center (VUMC) has identified several genetic factors associated with SARS-CoV-2 infection and severe COVID-19 illness.

Delirium and mortality reexamined

Jul. 8, 2021—A multicenter study of ICU patients found that in the hospital, delirium was associated with a nearly three-fold increase in risk of death the following day, but after discharge there was no association between delirium and mortality.

Genetics of hydrocephalus

Jul. 8, 2021—Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition.

Nobel laureate Doudna set for next Discovery Lecture

Jul. 7, 2021—Nobel laureate Jennifer Doudna, PhD, winner of the 2020 Vanderbilt Prize in Biomedical Science, will deliver the next web-based Discovery Lecture on Thursday, July 22.

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