acute kidney injury Archives
Machine learning aids injury prevention in cardiac cath labs
Feb. 2, 2023— by Paul Govern Acute kidney injury, or AKI, is a common complication of cardiac catheterization, posing higher costs, longer hospital stays and increased short-term and long-term mortality risk. In a large, randomized trial conducted over a period of 18 months at 19 medical centers of the Veterans Health Administration, a quality improvement implementation trial...
Novel therapeutic target identified for chronic kidney disease
Dec. 15, 2022—Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury.
Study compares kidney injury risk for COVID, flu patients
Mar. 17, 2022—A Vanderbilt study found that renin-angiotensin-aldosterone system (RAASi) inhibitor drugs, which are commonly used to regulate high blood pressure, do not disproportionately increase the risk of acute kidney injury (AKI) in patients with COVID-19 compared to patients hospitalized with influenza.
Gene variants increase risk of kidney failure in veterans of African ancestry with COVID-19: study
Feb. 10, 2022—Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19.
Protecting the injured kidney
Jun. 4, 2020—Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.
Protein levels in urine after acute kidney injury predict future loss of kidney function
Jan. 28, 2020—High levels of protein in a patient’s urine after acute kidney injury is associated with increased risk of kidney disease progression, Vanderbilt researchers report.
Acute kidney injury recovery time impacts future risk
Oct. 31, 2019—Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients.
Study: personalized decision support affects intensive care
Oct. 3, 2019—For patients in pediatric intensive care who are at high risk for acute kidney injury (AKI), giving clinicians automated decision support during the electronic order entry process increased the rate of blood testing for AKI by 9%.
New target for chronic kidney disease
Jan. 31, 2019—Preventing the formation of secretory structures that promote scarring in the kidney could offer new therapeutic options for a disease that affects millions of people worldwide.
YAP after acute kidney injury
Aug. 16, 2018—Activation of the signaling protein YAP may be a target for treating acute kidney injury, which affects up to 20 percent of hospitalized patients.
Study finds acetaminophen helps reduce acute kidney injury risk in children following cardiac surgery
May. 14, 2018—Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.
HDL and kidney injury after surgery
Jan. 17, 2018—Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.