Diabetes drug may improve asthma
Feb. 21, 2023—New biomarker finding strengthens the case for using GLP-1R agonists to treat patients with Type 2 diabetes who also suffer from asthma.
BMI genetics influence heart function
Jun. 16, 2022—Vanderbilt researchers have discovered that a genetic predisposition to elevated body mass index increases the risk of diastolic dysfunction — a cardiac condition that can lead to heart failure.
VUMC research team receives $1 million grant from AHA to study impact of long-COVID on heart
Apr. 14, 2022—A research team led by Cyndya Shibao, MD, MSCI, associate professor of Medicine at Vanderbilt University Medical Center (VUMC), has received a three-year, $1-million grant from the American Heart Association to study long-term effects of COVID-19 on the heart and cardiovascular system.
Peptides promote AFib arrhythmia
Apr. 11, 2022—Peptide oligomers have detrimental metabolic effects and cause pro-arrhythmic electrophysiological changes in heart atria, suggesting they may contribute to atrial fibrillation.
Vitamin D impact on disease biomarkers
Aug. 10, 2021—In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease.
American Heart Association honors Biaggioni’s research
Aug. 5, 2021—Italo Biaggioni, MD, professor of Medicine and Pharmacology, has been selected as a Distinguished Scientist of the American Heart Association for his contributions to cardiovascular and stroke research.
Probing statin-associated diseases with genetics
Jul. 12, 2021—Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.
Heat for hypertension in autonomic failure
May. 25, 2021—Heat therapy could offer a novel nonpharmacologic approach for treating the overnight hypertension that affects patients with autonomic failure.
HIV, diabetes and immune cells in fat
Mar. 18, 2021—In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes.
Gene variant and glucose metabolism
Feb. 18, 2021—Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.
Mitochondrial stress and hypertension
Jan. 12, 2021—Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.
Depression and the brain-age gap
Oct. 19, 2020—Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals.