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Aliquots Archives

Lean vs. obese adipose tissue cells

Dec. 13, 2018—A greater understanding of the mechanisms and cell types involved in returning adipose (fatty) tissue to the lean state may lead to more effective treatments for obesity.

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Breast cancer-killing RIG

Dec. 13, 2018—A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.

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The exocyst dynamo

Dec. 13, 2018—New methods have revealed details of vesicle trafficking in cells and are applicable to any protein complexes, potentially revolutionizing our understanding of cell dynamics.

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RNA processing and antiviral immunity

Dec. 13, 2018—John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.

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Analyzing single-cell landscapes

Nov. 29, 2018—Vanderbilt researchers have developed a new tool for quantifying data from single-cell studies.

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Green tea and diabetes

Nov. 29, 2018—In a large population study of Chinese adults, Vanderbilt researchers found that green tea drinking increased risk of type 2 diabetes.

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Lung cancer survival signal

Nov. 29, 2018—A receptor thought to be a cell growth inhibitor actually sends pro-survival signals in small cell lung cancer and is a candidate biomarker for poor prognosis.

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Parsing diabetic skin infections

Nov. 29, 2018—Vanderbilt researchers have discovered a role for an inflammatory mediator in diabetic skin infections, suggesting new therapeutic targets for this common complication of diabetes.

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Evading cell death

Nov. 8, 2018—Stress granules that form in response to cellular stress help cancer cells survive and develop resistance to treatment.

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Vitamin C protects brain from seizures

Nov. 8, 2018—Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.

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Novel methods to treat glaucoma

Nov. 8, 2018—Increasing a certain signaling molecule prevents the degeneration of retinal cells that are lost in glaucoma, suggesting a new way to treat this disease.

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Obesity negates beneficial drug effects

Nov. 8, 2018—A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.

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