Treating delirium detected in the ED
Mar. 7, 2023—Higher intensity physical or occupational therapy may be a useful intervention to shorten delirium duration in older hospitalized adults, Vanderbilt researchers recently reported.
Cell-free hemoglobin in pulmonary hypertension
Mar. 6, 2023—Cell-free hemoglobin generated by the lungs may be a therapeutic target for treating pulmonary arterial hypertension, Vanderbilt researchers found.
Sex counts in the brain as seasons change
Mar. 2, 2023—Photoperiod, or length of day, has sex-specific impacts on dopamine dynamics in the brain, offering insights into sex differences in neuropsychiatric disorders, Vanderbilt researchers report.
Sex-specific regulation of kidney signals
Mar. 2, 2023—Links between estrogen signaling and sodium excretion by the kidney could help explain a reduced risk of hypertension in females versus males.
Diabetes drug may improve asthma
Feb. 21, 2023—New biomarker finding strengthens the case for using GLP-1R agonists to treat patients with Type 2 diabetes who also suffer from asthma.
Probing hellbender health
Feb. 20, 2023—Understanding how hellbenders — large, fully aquatic salamanders — fight fungal pathogens and disease is important for protecting these unique stream predators; Vanderbilt researchers add new insights.
Breast cancer genetics: new insights
Feb. 16, 2023—Largest genetic study of breast cancer to date identifies 222 genetic risk loci, 137 genes and multiple signaling pathways associated with risk, providing important new insights.
Targeted therapy for neuroendocrine tumors
Feb. 16, 2023—Cancer therapies that target VEGF receptor appear safe and effective for patients with pancreatic and non-pancreatic neuroendocrine tumors, meta-analysis of phase 2/3 clinical trials demonstrates.
A new view of a cholesterol carrier
Feb. 7, 2023—Vanderbilt researchers developed a novel method to measure small RNAs carried by HDL and demonstrated that these molecules circulate in greater concentrations than previously believed and are likely to contribute to communication between immune cells.
Gut microbiota and lung fibrosis
Feb. 6, 2023—Microorganisms residing in the gut influence the severity of lung fibrosis in mouse models, suggesting that modifying the gut microbiota may offer therapeutic benefit for patients.
COVID-19 battle begins in the nose
Feb. 2, 2023—A high upper airway concentration of the virus that causes COVID-19 was associated with changes in gene expression that could impact disease progression, Vanderbilt researchers discovered.
Nutrient absorption disease model
Feb. 2, 2023—Vanderbilt researchers developed a model of a patient-specific mutation to explore the pathology of microvillus inclusion disease, a genetic disorder that causes life-threatening diarrhea.