Aliquots Archives
Probing H. pylori cancer protein
Feb. 14, 2019—Understanding how a bacterial protein that influences the risk of stomach cancer is produced could guide new strategies for treatment.
The yin and yang of cell signaling
Feb. 14, 2019—Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.
Modulating stress circuits
Feb. 14, 2019—Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.
Adhesion protein optimizes border
Feb. 14, 2019—Matthew Tyska and colleagues have found that an adhesion protein plays a key role in building the intestinal brush border that is essential for absorbing nutrients.
Destructive ‘telegrams’ in asthma
Jan. 31, 2019—Vanderbilt investigators have discovered that certain microRNAs — "telegram"-like signals — increase after the induction of allergic airway inflammation.
In utero antibiotics and obesity risk
Jan. 31, 2019—Maternal antibiotic use during pregnancy was not associated with childhood obesity at age 5, according a national study led by a Vanderbilt pediatrician.
Designing antibodies to fight the flu
Jan. 31, 2019—Vanderbilt investigators said their work shows that computational design can improve the ability of naturally occurring antibodies to recognize different flu strains and may hasten the development of more effective flu therapies and vaccines.
New target for chronic kidney disease
Jan. 31, 2019—Preventing the formation of secretory structures that promote scarring in the kidney could offer new therapeutic options for a disease that affects millions of people worldwide.
Signals from the “conveyor belt”
Jan. 17, 2019—Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.
Pain relievers a risk for C. diff?
Jan. 17, 2019—A link between anti-inflammatory drugs such as ibuprofen and C. diff infection suggests caution against overusing such drugs in patients at high risk for infection.
DNA’s on/off switch
Jan. 17, 2019—DNA-binding “switches” represent a fundamentally new method of communication between DNA-processing enzymes, Vanderbilt researchers propose.
Building a pancreas
Jan. 17, 2019—Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.
