Aliquots Archives
A biomarker for early Type 2 diabetes
Feb. 1, 2024—Genetic analyses suggest that branched chain amino acids may be a sensitive biomarker of early or subclinical Type 2 diabetes and could be used to identify risk and implement preventive measures.
Data haul improves immunotherapy response prediction
Jan. 16, 2024—Vanderbilt biostatisticians have developed an immunotherapy response model that outperforms existing predictive models.
Team uses COVID-19 to test automated acute disease profiling
Jan. 2, 2024—An automated solution for creating phenotyping algorithms, PheNorm, worked well to identify symptomatic COVID-19 cases in electronic health records, suggesting that automation could speed high-throughput phenotyping of acute disease.
Glucose metabolism influences B cell function
Dec. 29, 2023—Glucose metabolism influences the qualities of activated, mature B cells — white blood cells that are required for antibody-mediated immune responses, Vanderbilt researchers discovered.
Melanoma, anyone?
Dec. 19, 2023—Collegiate tennis and golf athletes aren’t using enough sunscreen according to a recent survey; meanwhile, the deadly skin cancer melanoma is on the rise.
Study examines social factors and cardiovascular disease risk
Dec. 18, 2023—Eight social factors were among the top 15 markers of cardiovascular disease risk and could help guide community prevention efforts, according to a new study using machine learning algorithms.
You missed a few: a better way to count health care-associated influenza cases
Dec. 8, 2023—The traditional definition of health care-associated influenza leads to gross undercounting, a Vanderbilt study suggests.
Pasteurization reduces bioactive component of breast milk
Dec. 6, 2023—Pasteurization of breast milk affects the concentration of osteopontin, a bioactive protein with roles in intestinal, immunological and brain development — suggesting that osteopontin supplementation should be considered when donor milk is provided to preterm infants.
Role of immunity in kidney injury hints at a potential therapy: study
Dec. 5, 2023—Targeting the cytokine IL-22 could be a new therapeutic approach to prevent kidney injury caused by drugs or toxins, Vanderbilt researchers have discovered.
Commensal gut bacterium protects from severe intestinal infection
Nov. 21, 2023— The commensal bacterium Turicibacter sanguinis could be used to protect against severe intestinal infections, Vanderbilt researchers discovered.
Nasty microbe H. pylori has Achilles’ heel
Nov. 16, 2023—Vanderbilt researchers found that an H. pylori enzyme is essential for colonization of the stomach, suggesting it as a promising therapeutic target for H. pylori infection.
Polygenic “scores” may improve cancer screening
Oct. 31, 2023—Accounting for genetic variability in biomarkers not associated with cancer risk could avoid unnecessary diagnostic procedures, Vanderbilt researchers found.