Aliquots Archives
Signals from the “conveyor belt”
Jan. 17, 2019—Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.
Pain relievers a risk for C. diff?
Jan. 17, 2019—A link between anti-inflammatory drugs such as ibuprofen and C. diff infection suggests caution against overusing such drugs in patients at high risk for infection.
DNA’s on/off switch
Jan. 17, 2019—DNA-binding “switches” represent a fundamentally new method of communication between DNA-processing enzymes, Vanderbilt researchers propose.
Building a pancreas
Jan. 17, 2019—Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.
Lean vs. obese adipose tissue cells
Dec. 13, 2018—A greater understanding of the mechanisms and cell types involved in returning adipose (fatty) tissue to the lean state may lead to more effective treatments for obesity.
Breast cancer-killing RIG
Dec. 13, 2018—A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.
The exocyst dynamo
Dec. 13, 2018—New methods have revealed details of vesicle trafficking in cells and are applicable to any protein complexes, potentially revolutionizing our understanding of cell dynamics.
RNA processing and antiviral immunity
Dec. 13, 2018—John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.
Analyzing single-cell landscapes
Nov. 29, 2018—Vanderbilt researchers have developed a new tool for quantifying data from single-cell studies.
Green tea and diabetes
Nov. 29, 2018—In a large population study of Chinese adults, Vanderbilt researchers found that green tea drinking increased risk of type 2 diabetes.
Lung cancer survival signal
Nov. 29, 2018—A receptor thought to be a cell growth inhibitor actually sends pro-survival signals in small cell lung cancer and is a candidate biomarker for poor prognosis.
Parsing diabetic skin infections
Nov. 29, 2018—Vanderbilt researchers have discovered a role for an inflammatory mediator in diabetic skin infections, suggesting new therapeutic targets for this common complication of diabetes.
