Aliquots Archives
MRI view of brain tumor prognosis
Feb. 22, 2021—In patients with glioblastoma brain tumors, features detected on MRIs at diagnosis were associated with survival, Vanderbilt Medical Center investigators found.
Genetic clues in eye birth defect
Feb. 18, 2021—Sabine Fuhrmann and colleagues have discovered a novel underlying cause of coloboma — a birth defect that causes missing tissue in the eye and accounts for up to 10% of childhood blindness.
Gene variant and glucose metabolism
Feb. 18, 2021—Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.
Imaging guidance for nerve repair
Feb. 9, 2021—A noninvasive, quantitative MRI method could be used after surgical repair of traumatic peripheral nerve injury to help clinicians make decisions about whether additional surgical interventions are needed.
Key factors in HIV-1 replication
Feb. 8, 2021—HIV-1, the virus that causes AIDS, exploits inositol phosphates in T cells to aid its own assembly and maturation — suggesting that targeting inositol phosphate binding could inhibit HIV-1 replication.
New clue to postural tachycardia
Feb. 4, 2021—Insight into the pathophysiology of an enigmatic and debilitating disease suggests new treatment approaches.
Gene network for leukemia factor
Feb. 4, 2021—A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment.
Rare tumor disguised as benign
Jan. 26, 2021—A rare tumor that causes facial weakness was found masquerading as a more common benign facial tumor.
An interacting factor in leukemia
Jan. 25, 2021—A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found.
Inflammation in genetic epilepsy
Jan. 21, 2021—Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments.
WIN for blocking cancer growth
Jan. 21, 2021—William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth.
Mitochondrial stress and hypertension
Jan. 12, 2021—Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.
