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Aliquots Archives

Autoimmunity advance

Aug. 24, 2021—Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments.

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Estrogen, depression and menopause

Aug. 23, 2021—A shift in emotional processing may help women adapt to lower estrogen after menopause —unless they have a history of major depressive disorder, Vanderbilt researchers have found.

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Potential protection from atherosclerosis

Aug. 19, 2021—Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins.

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Expression atlas for cell regulators

Aug. 19, 2021—Vanderbilt researchers report a comprehensive tissue-specific atlas of protein and mRNA expression for p63 and p73, members of the p53 family signaling network that is the most frequent target of mutations in human cancers.

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Vitamin D impact on disease biomarkers

Aug. 10, 2021—In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease.

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Sudden death from deep in the brain?

Aug. 9, 2021—Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy.

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Motor protein linked to intestinal cell differentiation

Aug. 5, 2021—The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered.

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Gene expression in diabetic nephropathy

Aug. 5, 2021—Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease.

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Prediction models for breast cancer

Jul. 27, 2021—Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction.

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Mood and cognition after chemotherapy

Jul. 26, 2021—Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report.

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Influenza network sizes up COVID

Jul. 22, 2021—Hospital data from a CDC network that monitors influenza revealed that adults hospitalized for COVID-19 in the early months of the pandemic were 20x more likely to die compared to hospitalized influenza patients.

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Establishing HIV care in Tennessee

Jul. 13, 2021—Vanderbilt researchers find that heterosexually active Black males are the least likely to establish HIV care within one month of diagnosis and suggest that targeted interventions focus on this population.

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