Aliquots Archives
New treatment for a rare obesity
Nov. 3, 2020—Diabetes drugs known as GLP-1 receptor agonists, such as exenatide (Byetta), are a promising and safe treatment for a rare form of obesity.
Frog peptides as anti-HIV microbicides
Nov. 2, 2020—Peptides derived from the antimicrobial peptides secreted by frogs could function as microbicides to limit HIV transmission, while sparing protective vaginal bacteria.
Histamine circuits in brain reward center
Oct. 29, 2020—Histamine — commonly associated with allergies — also has a signaling role in the brain’s reward center and may offer a novel target for treating addiction.
New markers of colorectal cancer risk
Oct. 29, 2020—Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo.
Preserving gut mucus architecture
Oct. 20, 2020—A new method that keeps microbes and gut cells together will be useful for studies of complex host-microbe interactions and for analysis of clinical specimens.
Depression and the brain-age gap
Oct. 19, 2020—Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals.
Possible COVID-19 “decoy”
Oct. 15, 2020—It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection.
Brain blood vessel response to hypoxia
Oct. 15, 2020—The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered.
Early steps in reovirus replication
Oct. 6, 2020—Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found.
Clue to diabetic kidney disease
Oct. 5, 2020—Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication.
Pinpointing brain changes in psychosis
Oct. 1, 2020—Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment.
Genes spell penicillin allergy risk
Oct. 1, 2020—Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction.
