Aliquots Archives
Blocking tumor ‘signals’ and ‘fuel’
Aug. 25, 2020—Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients.
Land of plenty (of opioids)
Aug. 24, 2020—Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction.
Salt, immune cells and hypertension
Aug. 20, 2020—Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption.
A “torque” for tumor blood vessels
Aug. 20, 2020—Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies.
Risk marker for repeat sinus surgery
Aug. 11, 2020—An inflammatory factor in mucus could be a biomarker of treatment-resistant chronic sinusitis used to determine which patients are at risk for repeat sinus surgery.
A step toward cancer prevention
Aug. 10, 2020—A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention.
ID of ‘stomach flu’ culprit
Aug. 6, 2020—Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines.
The importance of estrogen cycles
Aug. 6, 2020—Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.
Post-transplant complication
Jul. 28, 2020—Vanderbilt researchers conducted the largest analysis to date of a heart complication in children following stem cell transplant. The findings may help guide screening practices to improve outcomes.
Soy food, metabolism and the microbiome
Jul. 27, 2020—Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered.
Stomach bug hit-and-run
Jul. 23, 2020—The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate.
Cellular antiviral defenses
Jul. 23, 2020—A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Vanderbilt researchers have discovered it is also antiviral against DNA viruses.
