Diabetes drug may improve asthma
Feb. 21, 2023—New biomarker finding strengthens the case for using GLP-1R agonists to treat patients with Type 2 diabetes who also suffer from asthma.
Probing hellbender health
Feb. 20, 2023—Understanding how hellbenders — large, fully aquatic salamanders — fight fungal pathogens and disease is important for protecting these unique stream predators; Vanderbilt researchers add new insights.
Breast cancer genetics: new insights
Feb. 16, 2023—Largest genetic study of breast cancer to date identifies 222 genetic risk loci, 137 genes and multiple signaling pathways associated with risk, providing important new insights.
Targeted therapy for neuroendocrine tumors
Feb. 16, 2023—Cancer therapies that target VEGF receptor appear safe and effective for patients with pancreatic and non-pancreatic neuroendocrine tumors, meta-analysis of phase 2/3 clinical trials demonstrates.
A new view of a cholesterol carrier
Feb. 7, 2023—Vanderbilt researchers developed a novel method to measure small RNAs carried by HDL and demonstrated that these molecules circulate in greater concentrations than previously believed and are likely to contribute to communication between immune cells.
Gut microbiota and lung fibrosis
Feb. 6, 2023—Microorganisms residing in the gut influence the severity of lung fibrosis in mouse models, suggesting that modifying the gut microbiota may offer therapeutic benefit for patients.
COVID-19 battle begins in the nose
Feb. 2, 2023—A high upper airway concentration of the virus that causes COVID-19 was associated with changes in gene expression that could impact disease progression, Vanderbilt researchers discovered.
Nutrient absorption disease model
Feb. 2, 2023—Vanderbilt researchers developed a model of a patient-specific mutation to explore the pathology of microvillus inclusion disease, a genetic disorder that causes life-threatening diarrhea.
How arterial “stiffness” may impair cognition
Jan. 24, 2023—New findings from Vanderbilt neurologists suggest that cardiovascular disease may increase the spaces surrounding blood vessels in the brain and lead to cognitive decline.
Machine learning predicts delirium
Jan. 23, 2023—Using machine learning based on electronic health records of ICU patients predicted new-onset delirium with 82% sensitivity, Vanderbilt researchers found.
Is drinking tea good for your gut?
Jan. 19, 2023—Microbiome profiling of older Chinese adults showed that tea drinking changed the diversity and abundance of some bacteria in men but not women — effects that may contribute to a reduced risk of hypertension.
Low potassium injures kidney
Jan. 19, 2023—Vanderbilt researchers have discovered that low dietary potassium causes direct kidney injury, suggesting potential new targets for treating chronic kidney disease.