Aliquots Archives
Improved imaging for kidney disease
May. 8, 2023—Vanderbilt researchers identified optimal MRI parameters for estimating the severity of polycystic kidney disease, a common inherited disorder that can lead to end-stage renal failure.
Tracking lung macrophages
May. 4, 2023—A new technique will allow researchers to track subsets of immune cells that patrol and defend the lungs, to better understand the roles of these cells during lung inflammation, infection and injury.
Better adenoma detection
May. 4, 2023—Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans.
COVID alters respiratory microbiota
Apr. 25, 2023—COVID-19 infection alters the microbes of the upper respiratory tract for at least several weeks, and such disturbances could impact disease severity and be targets for therapeutic interventions.
Novel drugs have potential for treating tuberculosis
Apr. 24, 2023—Drug-resistant tuberculosis is on the rise, and novel antibacterial drugs called SPTs have potential for treating the deadly lung infection.
Overactive bladder and anxiety
Apr. 20, 2023—Anxiety and psychological stress impact hypersensitivity mechanisms in women that could contribute to overactive bladder — a frequent and sudden urge to urinate that is difficult to control.
Genetics and chronic pain
Apr. 20, 2023—Polygenic risk scores — scores that reflect the influence of common genetic variants — could be used to predict the likelihood of developing chronic overlapping pain conditions and guide biomarker and targeted prevention efforts.
COVID on Twitter: town vs. country
Apr. 11, 2023—A natural language processing analysis of 407 million tweets from May 2020 to January 2022 captures the rural-urban divide regarding COVID-19.
The problem with the problem list
Apr. 10, 2023—Algorithms to infer missing problems and suggest that they be added to electronic health records improved problem list completeness, with benefits for clinical care, patient comprehension of health conditions and population health.
COVID-19’s lingering impact on health
Apr. 6, 2023—A decline in cardiovascular fitness — measured by activity trackers in the All of Us research program — persisted among some groups even after COVID-related restrictions were relaxed, exacerbating health disparities.
A ‘supermere’ method for biomarker discovery
Apr. 6, 2023—Vanderbilt researchers have developed a method for isolating extracellular vesicles and nanoparticles — a complex transport system involved in health and disease — which will improve biomarker discovery and the identification of therapeutic targets.
Inflammation implicated in exfoliation syndrome
Mar. 28, 2023—Computational genetics tools have implicated inflammatory pathways in exfoliation syndrome, the most common cause of secondary glaucoma, which can result in blindness.
