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Aliquots Archives

COVID alters respiratory microbiota

Apr. 25, 2023—COVID-19 infection alters the microbes of the upper respiratory tract for at least several weeks, and such disturbances could impact disease severity and be targets for therapeutic interventions.

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Novel drugs have potential for treating tuberculosis

Apr. 24, 2023—Drug-resistant tuberculosis is on the rise, and novel antibacterial drugs called SPTs have potential for treating the deadly lung infection.

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Overactive bladder and anxiety

Apr. 20, 2023—Anxiety and psychological stress impact hypersensitivity mechanisms in women that could contribute to overactive bladder — a frequent and sudden urge to urinate that is difficult to control.

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Genetics and chronic pain

Apr. 20, 2023—Polygenic risk scores — scores that reflect the influence of common genetic variants — could be used to predict the likelihood of developing chronic overlapping pain conditions and guide biomarker and targeted prevention efforts.

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COVID on Twitter: town vs. country

Apr. 11, 2023—A natural language processing analysis of 407 million tweets from May 2020 to January 2022 captures the rural-urban divide regarding COVID-19.

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The problem with the problem list

Apr. 10, 2023—Algorithms to infer missing problems and suggest that they be added to electronic health records improved problem list completeness, with benefits for clinical care, patient comprehension of health conditions and population health.

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COVID-19’s lingering impact on health

Apr. 6, 2023—A decline in cardiovascular fitness — measured by activity trackers in the All of Us research program — persisted among some groups even after COVID-related restrictions were relaxed, exacerbating health disparities.

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A ‘supermere’ method for biomarker discovery

Apr. 6, 2023—Vanderbilt researchers have developed a method for isolating extracellular vesicles and nanoparticles — a complex transport system involved in health and disease — which will improve biomarker discovery and the identification of therapeutic targets.

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Inflammation implicated in exfoliation syndrome

Mar. 28, 2023—Computational genetics tools have implicated inflammatory pathways in exfoliation syndrome, the most common cause of secondary glaucoma, which can result in blindness.

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Improving lung nodule diagnosis

Mar. 27, 2023—Adding blood and imaging biomarkers to a clinical prediction model could improve diagnostic accuracy for the 1.6 million lung nodules detected each year, many through expanded lung cancer screening programs.

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Decoding cell division machinery

Mar. 23, 2023—Phosphate modification regulates the cell localization of Cdc15, one of the main controllers of cell division, to fine tune the assembly of cell division machinery.

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E. coli uses serine to abide acidity

Mar. 23, 2023—Vanderbilt researchers have discovered another acid resistance mechanism for UTI-causing E. coli, laying the foundation for targeted antibacterial therapies.

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