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Aliquots Archives

How arterial “stiffness” may impair cognition

Jan. 24, 2023—New findings from Vanderbilt neurologists suggest that cardiovascular disease may increase the spaces surrounding blood vessels in the brain and lead to cognitive decline.

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Machine learning predicts delirium

Jan. 23, 2023—Using machine learning based on electronic health records of ICU patients predicted new-onset delirium with 82% sensitivity, Vanderbilt researchers found.

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Is drinking tea good for your gut?

Jan. 19, 2023—Microbiome profiling of older Chinese adults showed that tea drinking changed the diversity and abundance of some bacteria in men but not women — effects that may contribute to a reduced risk of hypertension.

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Low potassium injures kidney

Jan. 19, 2023—Vanderbilt researchers have discovered that low dietary potassium causes direct kidney injury, suggesting potential new targets for treating chronic kidney disease.

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Anti-nausea drug response in children

Jan. 10, 2023—Genetic variation in a metabolic enzyme was not associated with response to the anti-nausea drug odansetron in children, Vanderbilt researchers report.

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Novel lung cancer biomarker

Jan. 9, 2023—Autoantibodies against the p53 tumor suppressor protein may be a novel biomarker for identifying people, especially African Americans, at high risk for lung cancer.

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Early effects of Huntington disease

Jan. 6, 2023—Impairments in brain executive function happen earlier than motor symptoms in people with the gene mutation that causes Huntington disease, suggesting younger ages and cognitive symptoms be considered for any future clinical trials.

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MicroRNAs linked to lipid damage

Jan. 6, 2023—VUMC researchers have linked microRNAs with systemic lipid peroxidation, a discovery that could point to new therapeutic targets for a variety of diseases.

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Risk score for muscular dystrophy

Nov. 22, 2022—An imaging-based risk score can identify patients with Duchenne muscular dystrophy who are at greater risk of early mortality, allowing more intensive treatment and potentially prolonging life.

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Suicide notes

Nov. 21, 2022—Natural language processing of notes in electronic health records can identify suicidal behavior and could be used to directly improve real-time risk prediction algorithms.

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Surgery for hereditary breast cancer

Nov. 17, 2022—Similar rates of bilateral mastectomy in women with inherited mutations in high- and moderate-penetrance genes raises concerns about possible overtreatment of some patients, Vanderbilt researchers report.

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A marker for mortality

Nov. 17, 2022—A urine biomarker of inflammation was associated with increased mortality and multiple lifestyle factors, suggesting that modifications could help reduce premature mortality.

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