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Aliquots Archives

Building a cohort, the easy way

Jan. 7, 2021—An automated system using keyword searches can help identify candidates for clinical trials on adverse drug reactions.

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A deeper look at out-of-home care

Dec. 15, 2020—Geographically targeted efforts to prevent children being placed in out-of-home care might be possible, Vanderbilt researchers report.

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Polymer protection for heart muscle

Dec. 14, 2020—Vanderbilt researchers demonstrate that the polymer P188 has promise as a therapy to prevent reperfusion injury — the cellular damage that occurs when blood flow returns after an ischemic event like a heart attack.

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Model students: improving clinical decision-making

Dec. 10, 2020—Vanderbilt investigators have devised a system to alert health IT teams to deteriorating performance in clinical prediction models.

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Exploiting viral vulnerabilities

Dec. 10, 2020—The isolation of human monoclonal antibodies against dangerous viruses including EEEV, Hendra and Nipah could offer new ways to treat and prevent these infections.

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A cohort for type 2 diabetes studies

Nov. 17, 2020—A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs.

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Imaging “biomarker” for Alzheimer’s disease progression

Nov. 16, 2020—Changes in connectivity in the brain’s white matter may be a novel neuroimaging biomarker for assessing Alzheimer’s disease progression.

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New therapeutic target for lung cancer

Nov. 12, 2020—Vanderbilt researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer.

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Breast cancer treatment in older women

Nov. 12, 2020—A new study from Vanderbilt epidemiologists suggests that it’s time to reconsider clinical practice guidelines for the treatment of early-stage breast cancer in older women.

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New treatment for a rare obesity

Nov. 3, 2020—Diabetes drugs known as GLP-1 receptor agonists, such as exenatide (Byetta), are a promising and safe treatment for a rare form of obesity.

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Frog peptides as anti-HIV microbicides

Nov. 2, 2020—Peptides derived from the antimicrobial peptides secreted by frogs could function as microbicides to limit HIV transmission, while sparing protective vaginal bacteria.

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Histamine circuits in brain reward center

Oct. 29, 2020—Histamine — commonly associated with allergies — also has a signaling role in the brain’s reward center and may offer a novel target for treating addiction.

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