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Aliquots Archives

New tools to study bioactive lipids

Jul. 14, 2020—Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction.

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“Nur” target may aid arthritis treatment

Jul. 13, 2020—Vanderbilt immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells.

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Recurrent UTIs linked to hidden reservoir

Jul. 9, 2020—Bacterial invasion of vaginal cells sets up a protective niche and a reservoir for recurrent urinary tract infections, Vanderbilt researchers demonstrated.

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Keeping beta cells “fit”

Jul. 9, 2020—Vanderbilt cell biologists are defining the factors that help beta cells in the pancreas stay healthy, secrete insulin and prevent diabetes initiation and progression.

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A connection to schizophrenia

Jun. 23, 2020—The insula, a small region of the brain involved in diverse brain functions had widespread dysconnectivity in schizophrenia, Vanderbilt researchers found.

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Single mutation causes seizure disorder

Jun. 22, 2020—A single mutation in one gene can impair inhibitory signaling in the brain and cause multiple types of seizures and behavioral abnormalities.

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Probing DNA damage repair

Jun. 18, 2020—After discovering a new mechanism for DNA damage repair last year, Vanderbilt biochemists now provide direct evidence for how it works.

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Studying cells in reduced dimensions

Jun. 18, 2020—Vanderbilt cell biologists have developed an unbiased, quantitative framework for evaluating single-cell data.

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Staph’s activation of blood clotting

Jun. 9, 2020—Staph bacteria may change the factor they use to activate blood clotting — to evade the immune response — a new study suggests.

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When rankings are unfounded

Jun. 8, 2020—There are many good reasons to survey anesthesiology patient satisfaction but ranking individual clinicians isn’t one of them, the authors of a new study conclude.

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Protecting the injured kidney

Jun. 4, 2020—Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

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Potential new cancer target

Jun. 4, 2020—Vanderbilt researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis.

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