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Aliquots Archives

Antibodies eye Pacific Island “fever”

May. 14, 2020—Vanderbilt Vaccine Center team isolates monoclonal antibodies against Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months.

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The adaptable anthrax bacterium

May. 14, 2020—Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.

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A dual-purpose metabolic switch

May. 5, 2020—John York and colleagues have demonstrated that the protein Vip1 is a rare type of bifunctional enzyme: it can both synthesize and destroy key cellular signaling molecules.

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The role of diet in esophageal cancer

May. 4, 2020—New findings suggest that dietary calcium and magnesium affect the risk of esophageal cancer; if confirmed in interventional studies, they could inform dietary modifications to reduce the burden of this cancer.

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EHRs, biobanks and Mendelian diseases

Apr. 30, 2020—Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis.

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Antibody finding raises hopes for Marburg, COVID-19 treatments

Apr. 30, 2020—Monoclonal antibodies against Marburg virus — a more lethal cousin of the RNA virus that causes COVID-19 — may aid in the development of antibody “cocktails” to counter viral infection.

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Reducing stress in parents of children with autism

Apr. 21, 2020—Parents of children with autism spectrum disorders benefited from the addition of mindfulness-based stress reduction to parent-implemented behavioral interventions.

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Damage, disruption, delirium

Apr. 20, 2020—New findings suggest that treatments that decrease oxidative damage might help with postoperative delirium that occurs in up to 30% of cardiac surgery patients.

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‘Tuning’ cell shape for division

Apr. 16, 2020—Dylan Burnette and colleagues have discovered that two forms of the molecular motor protein myosin have distinct roles in regulating cell shape during cell division.

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Transporter’s role in gut barrier

Apr. 16, 2020—A disease-associated mutation in a transporter protein impairs gut barrier function, leading to gastrointestinal disease and chronic infections.

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Spasticity underdiagnosed

Mar. 24, 2020—Spasticity — a consequence of stroke and other disorders of the central nervous system — may be underdiagnosed and undertreated in nursing home residents.

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Cellular factor helps package flu genome

Mar. 23, 2020—New insights on influenza genome packaging could guide strategies for interfering with the virus’s life cycle and ability to cause infection.

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