Aliquots Archives
Potential probe for early ovarian cancer
Jun. 20, 2019—Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.
Steroid binding to metabolic enzyme
Jun. 12, 2019—Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.
Cell-cell signals in developing heart
Jun. 10, 2019—Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.
Mouth microbes and colorectal cancer
Jun. 6, 2019—Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.
Treating core Rett syndrome symptoms
Jun. 6, 2019—A new study published in Neurology reports the drug trofinetide has proven safe and effective in treating core symptoms of Rett syndrome in female children and adolescents.
Line placement better with ultrasound
May. 9, 2019—Using ultrasound to place arterial lines reduces the need for surgical access and improves arterial line location, Vanderbilt researchers have found.
Frog fungus fights back
May. 9, 2019—Louise Rollins-Smith and colleagues are exploring how a deadly fungus counters the amphibian immune response and contributes to declining worldwide amphibian populations.
Blueprint for rebuilding the heart
May. 9, 2019—Young-Jae Nam and colleagues are discovering how to express specific factors in connective tissue cells to turn them into heart muscle cells.
The dynamic basement
May. 9, 2019—Vanderbilt scientists led by Andrea Page-McCaw have discovered a new way to analyze repair of basement membranes — important structural and functional components of tissues.
A new antibiotic’s mechanism of action
Apr. 25, 2019—Vanderbilt investigators have characterized how a new first-in-class antibacterial drug works, which will guide the development of additional compounds that overcome antibacterial resistance.
Immune ‘pruning’ in schizophrenia
Apr. 25, 2019—Ariel Deutch and colleagues have discovered that overactive brain immune cells during adolescence may contribute to schizophrenia.
Receptor’s role in stopping H. pylori
Apr. 25, 2019—The immune receptor NOD1 may be a prime target for preventing or treating H. pylori infections — the most significant risk factor for stomach cancer, Vanderbilt researchers have discovered.
