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Aliquots Archives

Target acquired for aggressive tumor

Sep. 27, 2012—New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified.

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Cell entry ports for cold virus

Sep. 25, 2012—The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells.

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HER2 may impact lung cancer therapy

Sep. 21, 2012—A protein associated with aggressive breast cancers may also influence resistance of lung cancer to targeted therapies.

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How ‘Jedi’ disposes of dead neurons

Sep. 19, 2012—The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system.

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Cells with LIP eat their neighbors

Sep. 13, 2012—A transcription factor called LIP is capable of causing one cell to consume another.

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Enzyme counters stomach acid attack

Sep. 11, 2012—Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.

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Parkinson’s therapy may impact language

Sep. 7, 2012—Deep brain stimulation used to treat Parkinson’s disease may impair some aspects of language processing, a recent study suggests.

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Neuronal subtypes in genetic disorder

Sep. 6, 2012—Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex.

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Targeting new pathways to ease pain

Aug. 30, 2012—The spinal cord’s neuropeptide Y signaling pathway may be a good target for new pain therapeutics.

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Clues to retinal cell degeneration

Aug. 28, 2012—A reversible chemical modification of rhodopsin, a receptor for light, plays a role in the degeneration of retinal cells.

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Tool helps plumb electronic records

Aug. 24, 2012—A tool developed for one institution’s electronic health records can work at other institutions, potentially facilitating the use of these records in research studies.

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Gene linked to familial prostate cancer

Aug. 23, 2012—A rare, inherited mutation confers an eightfold increased risk of prostate cancer, a recent study shows.

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