Aliquots Archives
Memory intact in early psychosis
Feb. 16, 2012—Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities.
On the tail of RSV infection mechanism
Feb. 15, 2012—New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly.
Matchmaker for clinical studies
Feb. 8, 2012—ResearchMatch.org is a web-based registry that is connecting participants and researchers for clinical studies.
Tool finds connections in genome data
Feb. 8, 2012—A new analytical tool points to genes that act together to increase disease risk.
Treatment window for genetic disorder
Feb. 1, 2012—Treatment with a drug used to prevent organ rejection partially reverses the course of tuberous sclerosis, research in mice suggests.
Drugs reverse lung cancer cell changes
Feb. 1, 2012—Drugs that target “epigenetic” changes may help treat or slow the progression of lung cancer.
Protein repairs esophageal DNA damage
Jan. 25, 2012—A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer.
Alcohol’s molecular mediators
Jan. 23, 2012—Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.
Pumping up the pancreas in pregnancy
Jan. 20, 2012—A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.
Obesity genes linked to uterine cancer
Jan. 20, 2012—In addition to body mass index, genetic markers of obesity may provide value in predicting endometrial cancer risk.
Fishing for heart attack repair tools
Jan. 5, 2012—Managing myocardial infarction – and the resulting heart failure – remains a clinical challenge. To search for chemicals that can stimulate cardiac muscle cell production, Vanderbilt Institute of Chemical Biology investigators led by Tao Zhong, Ph.D., Terri Ni, Ph.D., and Eric Rellinger, M.D., turned to a novel drug discovery tool: zebrafish. The researchers visually screened...
Clues to flattened faces
Jan. 5, 2012—Mutations in the Jagged1 gene cause Alagille syndrome, an inherited disorder that affects the liver, heart, kidneys and facial structure. Patients with Alagille syndrome often have a prominent forehead, a flattened midface and a prominent chin; some have a cleft palate. To investigate how mutations in Jagged1 cause facial anomalies, Steven Goudy, M.D., and colleagues...
