Aliquots Archives
Reprogramming cells for kidney repair
Mar. 14, 2019—Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.
Lighting up colorectal cancer
Feb. 28, 2019—A nanobeacon imaging agent that binds specifically to colorectal cancer cells may aid the early detection of cancer during colonoscopy.
Achilles’ heel for kidney cancer
Feb. 28, 2019—The discovery that kidney cells with mutations in a certain gene are sensitive to therapies called PI3K inhibitors opens new opportunities for applying precision medicine to cancer treatment.
Personalized pain management
Feb. 28, 2019—Understanding how natural brain chemicals with pain-relieving properties interact with administered opioids may guide personalized approaches for pain management.
Protein loss promotes cell migration
Feb. 28, 2019—The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.
Probing H. pylori cancer protein
Feb. 14, 2019—Understanding how a bacterial protein that influences the risk of stomach cancer is produced could guide new strategies for treatment.
The yin and yang of cell signaling
Feb. 14, 2019—Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.
Modulating stress circuits
Feb. 14, 2019—Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.
Adhesion protein optimizes border
Feb. 14, 2019—Matthew Tyska and colleagues have found that an adhesion protein plays a key role in building the intestinal brush border that is essential for absorbing nutrients.
Destructive ‘telegrams’ in asthma
Jan. 31, 2019—Vanderbilt investigators have discovered that certain microRNAs — "telegram"-like signals — increase after the induction of allergic airway inflammation.
In utero antibiotics and obesity risk
Jan. 31, 2019—Maternal antibiotic use during pregnancy was not associated with childhood obesity at age 5, according a national study led by a Vanderbilt pediatrician.
Designing antibodies to fight the flu
Jan. 31, 2019—Vanderbilt investigators said their work shows that computational design can improve the ability of naturally occurring antibodies to recognize different flu strains and may hasten the development of more effective flu therapies and vaccines.
