Aliquots Archives

AI maps routes to heart disease

Oct. 7, 2019—Machine learning on unlabeled electronic health record data has shed light on the emergence of cardiovascular disease.

A step toward gastric cancer

Oct. 3, 2019—New research findings provide insight into the detrimental events that develop in response to H. pylori infection.

A catalog of DNA replication proteins

Oct. 3, 2019—Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA.

Treating C. diff: new purpose for an old drug?

Sep. 24, 2019—An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.

Tailoring treatment for heart defect

Sep. 23, 2019—By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.

Microvilli in motion

Sep. 19, 2019—Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.

Potential prostate cancer biomarkers

Sep. 19, 2019—An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk.

Relational memory in early psychosis

Sep. 10, 2019—Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis.

Astrocytes and epilepsy

Sep. 9, 2019—A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report.

How salt increases blood pressure

Sep. 5, 2019—Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.

The plus and minus of microtubules

Sep. 5, 2019—Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer.