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American Cancer Society Archives

New prognosis predictor and target for gastric cancer

Apr. 7, 2022—The protein CGA — a subunit of glycoprotein hormones — is a biomarker that predicts chemoresistance in gastric cancer and could be targeted along with EGFR to restore chemosensitivity.

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Probing cancer cell invasion

Mar. 1, 2022—The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells.

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Diverticulitis surgery: guidelines needed

Feb. 10, 2022—Surgical removal of the colon for recurrent diverticulosis varies by geographic region and is associated with surgeon and hospital factors; stronger national guidelines are needed, Vanderbilt researchers report.

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Salmonella overcomes host resistance

Jan. 13, 2022—The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization.

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Thyroid cancer paper lands national recognition

Dec. 2, 2021—by Tom Wilemon A group of investigators in the Endocrine Neoplasia Research Laboratory at Vanderbilt University Medical Center has received national recognition for their work to discover better treatments for thyroid cancer. A paper describing their lab work was awarded first place in the Basic Science category at the 2021 Cancer Research Competition, which promotes...

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The role of polarity in early cancer

Sep. 21, 2021—Mutations in the protein epiregulin, an EGF receptor ligand, affect larger epithelial cell reorganization and may contribute to early cancer development, Vanderbilt researchers discovered.

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Study reveals missing link between high-fat diet, microbiota and heart disease

Aug. 12, 2021—A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

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Prostate cancer microenvironment

Mar. 23, 2021—Distinct cancer-associated fibroblasts in the prostate tumor microenvironment may influence tumor progression and could point to new therapeutic targets.

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Gene network for leukemia factor

Feb. 4, 2021—A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment.

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An interacting factor in leukemia

Jan. 25, 2021—A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found.

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Appendix cancer survival in young patients varies by race: study

Aug. 6, 2020—The first study of appendiceal cancer patterns and survival by race/ethnicity among patients younger than 50 in the U.S. showed survival disparities.

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Cellular antiviral defenses

Jul. 23, 2020—A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Vanderbilt researchers have discovered it is also antiviral against DNA viruses.

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