American Heart Association Archives

From left, Kimryn Rathmell, MD, PhD, Bradley Reinfeld, Matthew Madden and Jeffrey Rathmell, PhD, have discovered that immune cells — not cancer cells — are the major glucose consumers in the tumor microenvironment, upending a century-old observation.

Study revises understanding of cancer metabolism

Apr. 7, 2021—Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

HIV, diabetes and immune cells in fat

Mar. 18, 2021—In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes.

Eye stroke is focus of American Heart Association statement

Mar. 18, 2021—The American Heart Association (AHA) recently issued a scientific statement, “Management of Central Retinal Artery Occlusion.” CRAO is a form of ischemic stroke characterized by acute and painless vision loss in one eye.

Gene variant and glucose metabolism

Feb. 18, 2021—Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.

doctor checking patient's blood pressure

Mitochondrial stress and hypertension

Jan. 12, 2021—Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.

VHVI’s Brown, Agrawal receive American Heart Association awards

Dec. 10, 2020—Two Vanderbilt Heart and Vascular Institute researchers are receiving awards from the American Heart Association.

Depression and the brain-age gap

Oct. 19, 2020—Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals.

Heart Walk 2020

Sep. 24, 2020—The money is still rolling in, but the Greater Nashville Heart Walk has already raised $1.3 million in its fight against heart disease and stroke as well as to provide funding for public and professional education and community service programs.