antibiotic resistance Archives
Bacterial battle in 3D
Jun. 2, 2022—Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.
Probing pathogen antibiotic resistance
Sep. 17, 2020—Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics.
New space bolsters infectious disease and immunology discovery
Jul. 9, 2020—The Vanderbilt Institute for Infection, Immunology and Inflammation (VI4) recently moved into its new research and administrative home.
The adaptable anthrax bacterium
May. 14, 2020—Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.
Zinc uptake by a deadly pathogen
Jan. 13, 2020—The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.
Effort to remove penicillin allergy labels seeing success
Oct. 17, 2019—A program in the Medical Intensive Care Unit has successfully removed penicillin allergy labels from more than 45 inpatients at high risk to receive antibiotics, but whose penicillin allergies were low risk.
A new antibiotic’s mechanism of action
Apr. 25, 2019—Vanderbilt investigators have characterized how a new first-in-class antibacterial drug works, which will guide the development of additional compounds that overcome antibacterial resistance.
How bugs overcome host defenses
Apr. 11, 2019—Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”
New staph virulence factor
Jun. 28, 2018—Jun. 28, 2018—The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections.
Novel infection fighter
Jun. 13, 2018—A drug in use clinically to help make vaccines more effective may be a powerful new tool for fighting antibiotic-resistant infections.
Bacterial signaling systems
Feb. 3, 2017—Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.
Membrane fats impact drug transporter
Jul. 14, 2016—New studies of a membrane transporter could explain antibiotic resistance – and lead to novel ways to combat it.