antibiotic Archives
Novel drugs have potential for treating tuberculosis
Apr. 24, 2023—Drug-resistant tuberculosis is on the rise, and novel antibacterial drugs called SPTs have potential for treating the deadly lung infection.
Study advances understanding of bacterial bioterrorism agent
Apr. 7, 2022—Vanderbilt researchers have identified a critical regulatory factor in the bacterium that causes the disease anthrax and has been used as a biological weapon.
A new antibiotic’s mechanism of action
Apr. 25, 2019—Vanderbilt investigators have characterized how a new first-in-class antibacterial drug works, which will guide the development of additional compounds that overcome antibacterial resistance.
How bugs overcome host defenses
Apr. 11, 2019—Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”
In utero antibiotics and obesity risk
Jan. 31, 2019—Maternal antibiotic use during pregnancy was not associated with childhood obesity at age 5, according a national study led by a Vanderbilt pediatrician.
Study shows excess dietary zinc worsens C. diff infection
Sep. 26, 2016—Too much dietary zinc increases susceptibility to infection by Clostridium difficile — “C. diff” — the most common cause of hospital-acquired infections.
Bridging the antibiotic gap
Aug. 7, 2015—Vanderbilt researchers have discovered how certain molecules with antibiotic properties are synthesized, findings that could lead to new drugs that overcome the increased antibiotic resistance in bacteria.
Antibiotics with anticancer potential
Feb. 25, 2015—A series of experimental antibiotics may be a good starting point for developing new anticancer drugs.
Preserving antibiotic arsenal for TB
Oct. 30, 2013—Clinicians should be cautious about prescribing newer fluoroquinolone antibiotics to patients with TB risk factors; doing so may jeopardize the use of these agents against TB.
Studies outline new model for staph bone infections
Jun. 20, 2013—Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.
Bacterial resistance breaks bridges
Mar. 14, 2013—Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs.
Zinc: a new antibiotic target?
Jan. 17, 2013—It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.
