Preempting sudden cardiac death
Jul. 7, 2022—A technique to characterize all variants in genes associated with arrhythmia could improve the ability to identify and preemptively treat individuals at risk for sudden cardiac death.
A clue to an adverse drug event in children
May. 19, 2022—Considering metabolic (CYP2D6) enzyme activity score and patient age may aid in determining an individual’s risk for an adverse event with administration of the anti-arrhythmic drug propafenone.
Studies combine genetic testing, electronic health records to find undiagnosed diseases
Apr. 28, 2022—Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations.
VUMC researchers find clue to drug-induced arrhythmias
Feb. 24, 2022—Vanderbilt University Medical Center researchers have made a fundamental discovery about how the heart compensates for genetic variations that otherwise could trigger abnormal and potentially fatal heart rhythms.
Arrhythmia culprit: supertrafficking ion channel
Apr. 15, 2021—Charles Sanders, PhD, and colleagues show how a “supertrafficking” mutant potassium channel contributes to heart rhythm abnormalities.
Genotype looms large in risk for post-op arrhythmia
Mar. 11, 2021—Postoperative atrial fibrillation (PoAF), a form of arrhythmia, complicates 20-40% of cardiac surgical procedures and 10–20% of non-cardiac thoracic operations, cropping up two to four days after surgery to pose risk of stroke, heart attack, mortality, longer hospital stays and greater cost.
Robotic technology speeds arrhythmia gene classification
Jun. 12, 2020—Vanderbilt University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions.
VUMC receives portion of $14 million AHA award to study arrhythmias and sudden cardiac arrest
Jun. 26, 2019—VUMC receives more than $3.7 million from the American Heart Association to study cardiac arrhythmia and sudden cardiac arrest
Risk factors for faulty rhythms
Aug. 16, 2018—Risk factors for arrhythmias after heart surgery in infants include medications, infant age and higher surgical complexity, but not two genetic variants examined by Vanderbilt researchers.
New view of the heartbeat
Apr. 6, 2018—Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias.
VUMC testing device to reduce stroke risk in arrhythmia patients
Feb. 9, 2017—Vanderbilt University Medical Center (VUMC) is the first in the state to enroll patients in a clinical trial testing the effectiveness of the newest implantable device used to reduce stroke risk in patients with non-valvular atrial fibrillation (AF), the most common form of arrhythmia.
Knollmann to direct new arrhythmia research center
Jan. 14, 2016—Björn Knollmann, M.D., Ph.D., has been named director of the newly formed Vanderbilt Center for Arrhythmia Research and Therapeutics (VanCART).