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bacteria Archives

Team to study using probiotics to reduce heart disease risk

Feb. 3, 2022—A Vanderbilt research team has received a $7 million grant from the National Institutes of Health (NIH) to understand how alcohol’s effect on the gut microbiome drives heart disease.

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Caught in a web: study reveals that immune cells cooperate to trap and kill bacteria

Sep. 10, 2021—Vanderbilt researchers have identified a new antibacterial mechanism that could inspire novel strategies for combating staph and other extracellular bacterial pathogens.

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Probing innate immunity

May. 19, 2020—Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.

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New test assists physicians with quicker treatment decisions for sepsis

Oct. 3, 2019—Rapid blood culture diagnostics for patients with bacterial bloodstream infections delivered final results in 12 hours versus the two to three days required for conventional testing.

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A probiotic treatment for obesity?

Aug. 8, 2019—Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.

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Mouth microbes and colorectal cancer

Jun. 6, 2019—Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.

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How bugs overcome host defenses

Apr. 11, 2019—Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”

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Lighting up iron levels

Jan. 11, 2018—A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease.

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Predicting the infection response

Apr. 19, 2017—Vanderbilt investigators are probing the response to a bacterial toxin as a clinical assessment of immune function.

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Bacterial signaling systems

Feb. 3, 2017—Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.

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Slight chemical change may improve TB treatments: study

Feb. 11, 2016—One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered.

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Immune tolerance in endothelial cells

Jan. 7, 2016—Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis.

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