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beta cells Archives

Beta cell regeneration

May. 20, 2021—Vanderbilt researchers dissected the complex microenvironment of the pancreatic islet to discover the signals that drive beta cell regeneration — as a possible treatment for diabetes.

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Targeting glucagon action in diabetes

Mar. 4, 2021—Disrupting the action of glucagon — a pancreatic hormone that works to raise blood glucose — restores functional insulin-producing cells in mouse models of type 1 diabetes and may be a promising treatment strategy.

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Study sheds light on diabetes and COVID interaction

Dec. 10, 2020—COVID-19 has been linked to cases of new-onset diabetes, diabetes-related emergencies and a higher death rate among diabetes patients.

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Keeping beta cells “fit”

Jul. 9, 2020—Vanderbilt cell biologists are defining the factors that help beta cells in the pancreas stay healthy, secrete insulin and prevent diabetes initiation and progression.

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Building a pancreas

Jan. 17, 2019—Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.

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Beta cell biomarker findings may speed diabetes research

Nov. 29, 2018—Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding, reported this month in the journal Cell Metabolism, could lead to improved ways to study and treat diabetes.

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Cellular calcium handling in diabetes

Sep. 28, 2017—Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

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Therapeutic targets for diabetes

May. 3, 2017—Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes.

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Making human beta cells reproduce

Dec. 8, 2016—A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells.

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Fighting type 2 diabetes with FGF1

Nov. 18, 2015—The growth factor FGF1 induces the growth of new insulin-producing beta cells and may help treat type 2 diabetes.

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New therapeutic target for diabetes

Aug. 20, 2015—The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes.

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Boosting beta cells in diabetes

Apr. 20, 2015—New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.

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